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Attenuated Oxidative Stress following Acute Exhaustive Swimming Exercise Was Accompanied with Modified Gene Expression Profiles of Apoptosis in the Skeletal Muscle of Mice
المؤلفون المشاركون
Ji, Liu
Cui, Di
Ding, Shuzhe
Sun, Yi
Zhang, Zhe
Zhang, Tan
Shi, Jun
Jin, Haixiu
Ge, Zhe
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-10
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
The purpose of the present study was to investigate the effect of acute exhaustive swimming exercise on apoptosis in the skeletal muscle of mice.
Method.
C57BL/6 mice were averagely divided into seven groups.
One group was used as control (C), while the remaining six groups went through one-time exhaustive swimming exercise and were terminated at 0 h, 2 h, 6 h, 12 h, 24 h, and 48 h upon completion of exercise.
Result.
ABTS was significantly lowered at 12 h and 48 h after exercise.
The MDA level was significantly decreased at any time points sampled following exercise.
Total SOD activity was significantly decreased at 6 h, 12 h, 24 h, and 48 h after exercise.
Neither mRNA of Bax nor Bax/Bcl-2 ratio was significantly altered by exercise.
mRNA of Bcl-2 was significantly decreased since 6 h after exercise.
mRNA and protein expressions of PGC-1α were significantly increased at different time points following exercise.
Conclusion.
Cellular oxidative stress level was decreased following low intensity, long duration acute exhaustive swimming exercise in mice, and the enzymatic antioxidant capacity was compromised.
Apoptosis of the skeletal muscle was inhibited, which could partially be explained by the enhanced level of PGC-1α.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sun, Yi& Cui, Di& Zhang, Zhe& Zhang, Tan& Shi, Jun& Jin, Haixiu…[et al.]. 2016. Attenuated Oxidative Stress following Acute Exhaustive Swimming Exercise Was Accompanied with Modified Gene Expression Profiles of Apoptosis in the Skeletal Muscle of Mice. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1114354
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sun, Yi…[et al.]. Attenuated Oxidative Stress following Acute Exhaustive Swimming Exercise Was Accompanied with Modified Gene Expression Profiles of Apoptosis in the Skeletal Muscle of Mice. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1114354
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sun, Yi& Cui, Di& Zhang, Zhe& Zhang, Tan& Shi, Jun& Jin, Haixiu…[et al.]. Attenuated Oxidative Stress following Acute Exhaustive Swimming Exercise Was Accompanied with Modified Gene Expression Profiles of Apoptosis in the Skeletal Muscle of Mice. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1114354
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114354
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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