Novel heterocycles based on 1, 3, 4-thiadiazole scaffold as insecticides

الملخص EN

The crop plants are the major source of human nutrition, but insects and pests cause huge economic losses every year.

The authors were interested in developing novel insecticidal agents with low toxicity and an acceptable impact on the environment.

Thus, 2-amino-5-(substituted)-1, 3, 4-thiadiazoles (1a, b) were used as versatile materials to synthesize novel compounds through reaction with different electrophiles.

The insecticidal activity of the synthesized compounds was tested using 4th instar larvae of spodoptera littoralis.

Most of the tested compounds showed good to excellent insecticidal activity.

Thus, the synthesized compounds could be used in the field of pest control through using them in proper pesticide formulations.