Behavior of Oxidative Stress Markers in Alcoholic Liver Cirrhosis Patients
المؤلفون المشاركون
Cordero-Pérez, Paula
Muñoz-Espinosa, Linda E.
Galicia-Moreno, Marina
Rosique-Oramas, Dorothy
Medina-Avila, Zaira
Álvarez-Torres, Tania
Falcón, Dalia
Higuera-de la tijera, Fátima
Béjar, Yadira L.
Pérez-Hernández, José Luis
Kershenobich, David
Gutierrez-Reyes, Gabriela
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-15
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Alcohol is the most socially accepted addictive substance worldwide, and its metabolism is related with oxidative stress generation.
The aim of this work was to evaluate the role of oxidative stress in alcoholic liver cirrhosis (ALC).
This study included 187 patients divided into two groups: ALC, classified according to Child-Pugh score, and a control group.
We determined the levels of reduced and oxidized glutathione (GSH and GSSG) and the GSH/GSSG ratio by an enzymatic method in blood.
Also, protein carbonyl and malondialdehyde (MDA) content were estimated in serum.
MDA levels increased in proportion to the severity of damage, whereas the GSH and GSSG levels decreased and increased, respectively, at different stages of cirrhosis.
There were no differences in the GSH/GSSG ratio and carbonylated protein content between groups.
We also evaluated whether the active consumption of or abstinence from alcoholic beverages affected the behavior of these oxidative markers and only found differences in the MDA, GSH, and GSSG determination and the GSH/GSSG ratio.
Our results suggest that alcoholic cirrhotic subjects have an increase in oxidative stress in the early stages of disease severity and that abstinence from alcohol consumption favors the major antioxidant endogen: GSH in patients with advanced disease severity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Galicia-Moreno, Marina& Rosique-Oramas, Dorothy& Medina-Avila, Zaira& Álvarez-Torres, Tania& Falcón, Dalia& Higuera-de la tijera, Fátima…[et al.]. 2016. Behavior of Oxidative Stress Markers in Alcoholic Liver Cirrhosis Patients. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1114759
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Galicia-Moreno, Marina…[et al.]. Behavior of Oxidative Stress Markers in Alcoholic Liver Cirrhosis Patients. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1114759
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Galicia-Moreno, Marina& Rosique-Oramas, Dorothy& Medina-Avila, Zaira& Álvarez-Torres, Tania& Falcón, Dalia& Higuera-de la tijera, Fátima…[et al.]. Behavior of Oxidative Stress Markers in Alcoholic Liver Cirrhosis Patients. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1114759
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114759
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر