Impact of Sex on the Nonmotor Symptoms and the Health-Related Quality of Life in Parkinson’s Disease
المؤلفون المشاركون
Kovács, Norbert
Weintraut, Rita
Janszky, József
Makkos, Attila
Komoly, Sámuel
Kovács, Márton
Aschermann, Zsuzsanna
Karádi, Kázmér
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-16
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background.
Female Parkinson’s disease (PD) patients seem to experience not only more severe motor complications and postural instability but also more pronounced depression, anxiety, pain, and sleep disturbances.
Objective.
The aim of the present study was to evaluate the role of sex as a possible independent predictor of HRQoL in PD.
Methods.
In this cross-sectional study, 621 consecutive patients treated at the University of Pécs were enrolled.
Severity of PD symptoms was assessed by MDS-UPDRS, UDysRS, Non-Motor Symptoms Scale, PDSS-2, Hamilton Anxiety Scale, Montgomery-Asberg Depression Rating Scale, Lille Apathy Rating Scale, and Addenbrooke Cognitive Examination.
HRQoL was assessed by PDQ-39 and EQ-5D.
Multiple regression analysis was performed to estimate the PDQ-39 and EQ-5D index values based on various clinical factors.
Results.
Although females received significantly lower dosage of levodopa, they had significantly more disabling dyskinesia and worse postural instability.
Anxiety, pain, sleep disturbances, and orthostatic symptoms were more frequent among females while sexual dysfunction, apathy, and daytime sleepiness were more severe among males.
Women had worse HRQoL than men (EQ-5D index value: 0.620 ± 0.240 versus 0.663 ± 0.229 , p = 0.025 , and PDQ-39 SI: 27.1 ± 17.0 versus 23.5 ± 15.9 , p = 0.010 ).
Based on multiple regression analysis, sex was an independent predictor for HRQoL in PD.
Conclusions.
Based on our results, female sex is an independent predictor for having worse HRQoL in PD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kovács, Márton& Makkos, Attila& Aschermann, Zsuzsanna& Janszky, József& Komoly, Sámuel& Weintraut, Rita…[et al.]. 2016. Impact of Sex on the Nonmotor Symptoms and the Health-Related Quality of Life in Parkinson’s Disease. Parkinson’s Disease،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1115267
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kovács, Márton…[et al.]. Impact of Sex on the Nonmotor Symptoms and the Health-Related Quality of Life in Parkinson’s Disease. Parkinson’s Disease No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1115267
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kovács, Márton& Makkos, Attila& Aschermann, Zsuzsanna& Janszky, József& Komoly, Sámuel& Weintraut, Rita…[et al.]. Impact of Sex on the Nonmotor Symptoms and the Health-Related Quality of Life in Parkinson’s Disease. Parkinson’s Disease. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1115267
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1115267
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر