Using Tractography to Distinguish SWEDD from Parkinson’s Disease Patients Based on Connectivity
المؤلفون المشاركون
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-29
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
It is critical to distinguish between Parkinson’s disease (PD) and scans without evidence of dopaminergic deficit (SWEDD), because the two groups are different and require different therapeutic approaches.
Objective.
The aim of this study was to distinguish SWEDD patients from PD patients using connectivity information derived from diffusion tensor imaging tractography.
Methods.
Diffusion magnetic resonance images of SWEDD ( n = 37 ) and PD ( n = 40 ) were obtained from a research database.
Tractography, the process of obtaining neural fiber information, was performed using custom software.
Group-wise differences between PD and SWEDD patients were quantified using the number of connected fibers between two regions, and correlation analyses were performed based on clinical scores.
A support vector machine classifier (SVM) was applied to distinguish PD and SWEDD based on group-wise differences.
Results.
Four connections showed significant group-wise differences and correlated with the Unified Parkinson’s Disease Rating Scale sponsored by the Movement Disorder Society.
The SVM classifier attained 77.92% accuracy in distinguishing between SWEDD and PD using these identified connections.
Conclusions.
The connections and regions identified represent candidates for future research investigations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Mansu& Park, Hyunjin. 2016. Using Tractography to Distinguish SWEDD from Parkinson’s Disease Patients Based on Connectivity. Parkinson’s Disease،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1115272
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Mansu& Park, Hyunjin. Using Tractography to Distinguish SWEDD from Parkinson’s Disease Patients Based on Connectivity. Parkinson’s Disease No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1115272
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Mansu& Park, Hyunjin. Using Tractography to Distinguish SWEDD from Parkinson’s Disease Patients Based on Connectivity. Parkinson’s Disease. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1115272
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1115272
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر