An Integrated Review of Psychological Stress in Parkinson’s Disease: Biological Mechanisms and Symptom and Health Outcomes
المؤلفون المشاركون
Austin, Kim Wieczorek
Ameringer, Suzanne Weil
Cloud, Leslie Jameleh
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-12
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Parkinson’s disease (PD) is characterized by complex symptoms and medication-induced motor complications that fluctuate in onset, severity, responsiveness to treatment, and disability.
The unpredictable and debilitating nature of PD and the inability to halt or slow disease progression may result in psychological stress.
Psychological stress may exacerbate biological mechanisms believed to contribute to neuronal loss in PD and lead to poorer symptom and health outcomes.
The purpose of this integrated review is to summarize and appraise animal and human research studies focused on biological mechanisms, symptom, and health outcomes of psychological stress in PD.
A search of the electronic databases PubMed/Medline and CINAHL from 1980 to the present using the key words Parkinson’s disease and stress, psychological stress, mental stress, and chronic stress resulted in 11 articles that met inclusion criteria.
The results revealed significant associations between psychological stress and increased motor symptom severity and loss of dopamine-producing neurons in animal models of PD and between psychological stress and increased symptom severity and poorer health outcomes in human subjects with PD.
Further research is needed to fully elucidate the underlying biological mechanisms responsible for these relationships, for the ultimate purpose of designing targeted interventions that may modify the disease trajectory.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Austin, Kim Wieczorek& Ameringer, Suzanne Weil& Cloud, Leslie Jameleh. 2016. An Integrated Review of Psychological Stress in Parkinson’s Disease: Biological Mechanisms and Symptom and Health Outcomes. Parkinson’s Disease،Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1115288
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Austin, Kim Wieczorek…[et al.]. An Integrated Review of Psychological Stress in Parkinson’s Disease: Biological Mechanisms and Symptom and Health Outcomes. Parkinson’s Disease No. 2016 (2016), pp.1-15.
https://search.emarefa.net/detail/BIM-1115288
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Austin, Kim Wieczorek& Ameringer, Suzanne Weil& Cloud, Leslie Jameleh. An Integrated Review of Psychological Stress in Parkinson’s Disease: Biological Mechanisms and Symptom and Health Outcomes. Parkinson’s Disease. 2016. Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1115288
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1115288
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر