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A Comparison of Oxycodone and Alfentanil in Intravenous Patient-Controlled Analgesia with a Time-Scheduled Decremental Infusion after Laparoscopic Cholecystectomy
المؤلفون المشاركون
Kwon, Young Suk
Jang, Ji Su
Lee, Na Rea
Kim, Seong Su
Kim, Young Ki
Hwang, Byeong Mun
Kang, Seong Sik
Son, Hee Jeong
Lim, So Young
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Oxycodone, a semisynthetic opioid, has been widely used for acute and chronic pain.
Objectives.
The aim of this study was to compare the analgesic and adverse effects of oxycodone and alfentanil on postoperative pain after laparoscopic cholecystectomy.
Methods.
This was a prospective, randomized, double-blind study.
A total of 82 patients undergoing laparoscopic cholecystectomy were randomly assigned to receive either oxycodone or alfentanil using intravenous patient-controlled analgesia (PCA).
PCA was administered as a time-scheduled decremental continuous infusion based on lean body mass for 48 hours postoperatively.
Patients were assessed for pain with a visual analogue scale (VAS), the cumulative PCA dose, adverse effects, sedation level at 1, 4, 8, 16, 24, and 48 hours postoperatively, and satisfaction during the postoperative 48 hours.
Results.
There were no significant differences (p<0.05) between the two groups in VAS score, cumulative PCA dose, adverse effects, sedation level at 1, 4, 8, 16, 24, and 48 hours postoperatively, and satisfaction during the postoperative 48 hours.
Conclusions.
Our data showed that the analgesic and adverse effects of oxycodone and alfentanil were similar.
Therefore, oxycodone may be a good alternative to alfentanil for pain management using intravenous PCA after laparoscopic cholecystectomy when used at a conversion ratio of 10 : 1.
This trial is registered with KCT0001962.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kwon, Young Suk& Jang, Ji Su& Lee, Na Rea& Kim, Seong Su& Kim, Young Ki& Hwang, Byeong Mun…[et al.]. 2016. A Comparison of Oxycodone and Alfentanil in Intravenous Patient-Controlled Analgesia with a Time-Scheduled Decremental Infusion after Laparoscopic Cholecystectomy. Pain Research and Management،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1115502
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kwon, Young Suk…[et al.]. A Comparison of Oxycodone and Alfentanil in Intravenous Patient-Controlled Analgesia with a Time-Scheduled Decremental Infusion after Laparoscopic Cholecystectomy. Pain Research and Management No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1115502
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kwon, Young Suk& Jang, Ji Su& Lee, Na Rea& Kim, Seong Su& Kim, Young Ki& Hwang, Byeong Mun…[et al.]. A Comparison of Oxycodone and Alfentanil in Intravenous Patient-Controlled Analgesia with a Time-Scheduled Decremental Infusion after Laparoscopic Cholecystectomy. Pain Research and Management. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1115502
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1115502
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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