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Effect of Intravenous High Dose Vitamin C on Postoperative Pain and Morphine Use after Laparoscopic Colectomy: A Randomized Controlled Trial
المؤلفون المشاركون
Jeon, Younghoon
Park, Jun Seok
Moon, Suyoung
Yeo, Jinseok
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background and Objective.
Vitamin C has antioxidant, neuroprotective, and neuromodulating effects.
Recently, it showed antinociceptive effect as a result of the antioxidant properties.
Therefore, we designed this study to assess the effect of intravenous vitamin C on opiate consumption and pain in patients undergoing laparoscopic colectomy.
Methods.
A total of 100 patients were enrolled and allocated to receive 50 mg/kg vitamin C or placebo by intravenous infusion immediately after induction of anesthesia.
Morphine consumption and scores of pain were assessed at 2, 6, and 24 h after completion of surgery.
Results.
There were 97 patients included in the analysis.
Patients who received vitamin C had higher plasma concentrations of vitamin C at the end of surgery, significantly lower morphine consumption at the 2 h after end of surgery, and significantly lower pain scores at rest during first 24 h postoperatively.
There was no significant difference between groups in side effects, fatigue score, or pain score during cough.
Conclusion.
This study shows high dose vitamin C infusion decreased postoperative pain during the first 24 h and reduced morphine consumption in the early postoperative period.
Additional research needed to examine whether higher doses of vitamin C and longer infusion times can amplify these effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jeon, Younghoon& Park, Jun Seok& Moon, Suyoung& Yeo, Jinseok. 2016. Effect of Intravenous High Dose Vitamin C on Postoperative Pain and Morphine Use after Laparoscopic Colectomy: A Randomized Controlled Trial. Pain Research and Management،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1115517
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jeon, Younghoon…[et al.]. Effect of Intravenous High Dose Vitamin C on Postoperative Pain and Morphine Use after Laparoscopic Colectomy: A Randomized Controlled Trial. Pain Research and Management No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1115517
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jeon, Younghoon& Park, Jun Seok& Moon, Suyoung& Yeo, Jinseok. Effect of Intravenous High Dose Vitamin C on Postoperative Pain and Morphine Use after Laparoscopic Colectomy: A Randomized Controlled Trial. Pain Research and Management. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1115517
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1115517
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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