Cognitive Function before and during Treatment with Selective Serotonin Reuptake Inhibitors in Patients with Depression or Obsessive-Compulsive Disorder
المؤلفون المشاركون
Kouti, Leila
Sayyah, Mehdi
Eslami, Kaveh
AlaiShehni, Shabnam
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-15
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
علم النفس
الطب البشري
الطب النفسي
الملخص EN
Objectives.
Identification of adverse effects of selective serotonin reuptake inhibitors (SSRIs) is of great importance due to their extensive use in medicine.
Some studies have reported the effects of SSRIs on cognitive functions, but the results are conflicting.
This study was designed to assess the effect of these drugs on cognition of patients with depression or obsessive-compulsive disorder (OCD).
Methods.
Patients with depression or OCD, naïve to therapy, and candidates of receiving one drug from SSRI class, voluntarily, entered this study.
Mini-Mental State Examination (MMSE) test was the tool to assess their cognitive functions.
MMSE scores of each patient were recorded prior to taking SSRIs and at weeks 3, 5, and 8 of drug therapy.
Results.
50 patients met our inclusion criteria, with a baseline mean MMSE score of 23.94.
At 3, 5, and 8 weeks of treatment, the mean scores were 22.1, 21.4, and 20.66, respectively.
With a p value of <0.0001, the gradual decline was statistically significant.
Conclusion.
The MMSE scores of our patients showed a gradual decline over the consecutive weeks after taking SSRI drugs.
It seems that the use of SSRIs in patients with depression or OCD, can cause cognitive dysfunction in the acute phase of treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sayyah, Mehdi& Eslami, Kaveh& AlaiShehni, Shabnam& Kouti, Leila. 2016. Cognitive Function before and during Treatment with Selective Serotonin Reuptake Inhibitors in Patients with Depression or Obsessive-Compulsive Disorder. Psychiatry Journal،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1115618
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sayyah, Mehdi…[et al.]. Cognitive Function before and during Treatment with Selective Serotonin Reuptake Inhibitors in Patients with Depression or Obsessive-Compulsive Disorder. Psychiatry Journal No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1115618
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sayyah, Mehdi& Eslami, Kaveh& AlaiShehni, Shabnam& Kouti, Leila. Cognitive Function before and during Treatment with Selective Serotonin Reuptake Inhibitors in Patients with Depression or Obsessive-Compulsive Disorder. Psychiatry Journal. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1115618
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1115618
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر