Muscle Satellite Cells: Exploring the Basic Biology to Rule Them
المؤلفون المشاركون
Vainzof, Mariz
Fernandes, Stephanie A.
Keith Okamoto, Oswaldo
Almeida, Camila F.
Ribeiro Junior, Antonio F.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-03
دولة النشر
مصر
عدد الصفحات
14
الملخص EN
Adult skeletal muscle is a postmitotic tissue with an enormous capacity to regenerate upon injury.
This is accomplished by resident stem cells, named satellite cells, which were identified more than 50 years ago.
Since their discovery, many researchers have been concentrating efforts to answer questions about their origin and role in muscle development, the way they contribute to muscle regeneration, and their potential to cell-based therapies.
Satellite cells are maintained in a quiescent state and upon requirement are activated, proliferating, and fusing with other cells to form or repair myofibers.
In addition, they are able to self-renew and replenish the stem pool.
Every phase of satellite cell activity is highly regulated and orchestrated by many molecules and signaling pathways; the elucidation of players and mechanisms involved in satellite cell biology is of extreme importance, being the first step to expose the crucial points that could be modulated to extract the optimal response from these cells in therapeutic strategies.
Here, we review the basic aspects about satellite cells biology and briefly discuss recent findings about therapeutic attempts, trying to raise questions about how basic biology could provide a solid scaffold to more successful use of these cells in clinics.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Almeida, Camila F.& Fernandes, Stephanie A.& Ribeiro Junior, Antonio F.& Keith Okamoto, Oswaldo& Vainzof, Mariz. 2016. Muscle Satellite Cells: Exploring the Basic Biology to Rule Them. Stem Cells International،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1115968
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Almeida, Camila F.…[et al.]. Muscle Satellite Cells: Exploring the Basic Biology to Rule Them. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1115968
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Almeida, Camila F.& Fernandes, Stephanie A.& Ribeiro Junior, Antonio F.& Keith Okamoto, Oswaldo& Vainzof, Mariz. Muscle Satellite Cells: Exploring the Basic Biology to Rule Them. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1115968
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1115968
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر