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Applications of Mesenchymal Stem Cells and Neural Crest Cells in Craniofacial Skeletal Research
المؤلفون المشاركون
Morikawa, Satoru
Ouchi, Takehito
Shibata, Shinsuke
Fujimura, Takumi
Kawana, Hiromasa
Nakagawa, Taneaki
Okano, Hideyuki
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-24
دولة النشر
مصر
عدد الصفحات
8
الملخص EN
Craniofacial skeletal tissues are composed of tooth and bone, together with nerves and blood vessels.
This composite material is mainly derived from neural crest cells (NCCs).
The neural crest is transient embryonic tissue present during neural tube formation whose cells have high potential for migration and differentiation.
Thus, NCCs are promising candidates for craniofacial tissue regeneration; however, the clinical application of NCCs is hindered by their limited accessibility.
In contrast, mesenchymal stem cells (MSCs) are easily accessible in adults, have similar potential for self-renewal, and can differentiate into skeletal tissues, including bones and cartilage.
Therefore, MSCs may represent good sources of stem cells for clinical use.
MSCs are classically identified under adherent culture conditions, leading to contamination with other cell lineages.
Previous studies have identified mouse- and human-specific MSC subsets using cell surface markers.
Additionally, some studies have shown that a subset of MSCs is closely related to neural crest derivatives and endothelial cells.
These MSCs may be promising candidates for regeneration of craniofacial tissues from the perspective of developmental fate.
Here, we review the fundamental biology of MSCs in craniofacial research.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Morikawa, Satoru& Ouchi, Takehito& Shibata, Shinsuke& Fujimura, Takumi& Kawana, Hiromasa& Okano, Hideyuki…[et al.]. 2016. Applications of Mesenchymal Stem Cells and Neural Crest Cells in Craniofacial Skeletal Research. Stem Cells International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1116311
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Morikawa, Satoru…[et al.]. Applications of Mesenchymal Stem Cells and Neural Crest Cells in Craniofacial Skeletal Research. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1116311
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Morikawa, Satoru& Ouchi, Takehito& Shibata, Shinsuke& Fujimura, Takumi& Kawana, Hiromasa& Okano, Hideyuki…[et al.]. Applications of Mesenchymal Stem Cells and Neural Crest Cells in Craniofacial Skeletal Research. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1116311
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1116311
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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