Induced Pluripotent Stem Cells and Outer Retinal Disease

المؤلفون المشاركون

Yang, Jin
Cai, Bingcui
Glencer, Patrick
Li, Zhiqing
Zhang, Xiaomin
Li, Xiaorong

المصدر

Stem Cells International

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-01-05

دولة النشر

مصر

عدد الصفحات

6

الملخص EN

The retina, which is composed of multiple layers of differing cell types, has been considered the first choice for gene therapy, disease modeling, and stem cell-derived retinal cell transplant therapy.

Because of its special characteristics, the retina, located in the posterior part of the eye, can be well observed directly after gene therapy or transplantation.

The blood-retinal barrier is part of a specialized ocular microenvironment that is immune privileged.

This protects transplanted cells and tissue.

Having two eyes makes perfect natural control possible after a single eye receives gene or stem cell therapy.

For this reason, research about exploring retinal diseases’ underlying molecular mechanisms and potential therapeutic approach using stem cell technique has been developing rapidly.

This review is to present an up-to-date summary of the iPSC’s sources, variations, differentiation methods, and the wide-ranging application of iPSCs-RPCS or iPSCs-RPE on retinal disease modeling, diagnostics, and therapeutics.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Yang, Jin& Cai, Bingcui& Glencer, Patrick& Li, Zhiqing& Zhang, Xiaomin& Li, Xiaorong. 2016. Induced Pluripotent Stem Cells and Outer Retinal Disease. Stem Cells International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1116312

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Yang, Jin…[et al.]. Induced Pluripotent Stem Cells and Outer Retinal Disease. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1116312

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Yang, Jin& Cai, Bingcui& Glencer, Patrick& Li, Zhiqing& Zhang, Xiaomin& Li, Xiaorong. Induced Pluripotent Stem Cells and Outer Retinal Disease. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1116312

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1116312