Role of Mast Cells in Oral Lichen Planus and Oral Lichenoid Reactions
المؤلفون المشاركون
Narasimhan, Malathi
Suganya, Ramalingam
Thamizhchelvan, Harikrishnan
Sangeetha, Narasimhan
Rajan, Sharada T
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-17
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction.
Oral lichen planus (OLP) is a chronic T cell mediated disease of oral mucosa, skin, and its appendages with a prevalence of 0.5 to 2.6% worldwide.
Oral lichenoid reactions (OLR) are a group of lesions with diverse aetiologies but have clinical and histological features similar to OLP, thereby posing a great challenge in differentiating both lesions.
Mast cells are multifunctional immune cells that play a major role in the pathogenesis of lichen planus by release of certain chemical mediators.
Increased mast cell densities with significant percentage of degranulation have been observed as a consistent finding in pathogenesis of oral lichen planus.
Aim.
The current study was aimed at quantifying the mast cells in histopathological sections of OLP and OLR thereby aiding a means of distinguishing these lesions.
Materials and Methods.
The study group involved 21 cases of oral lichen planus, 21 cases of oral lichenoid reactions, and 10 control specimens of normal buccal mucosa.
All the cases were stained with Toluidine Blue and routine haematoxylin and eosin and the mast cells were quantified.
Statistical Analysis Used.
The results were analyzed using the Kruskal–Wallis test and an intergroup analysis was performed using Mann–Whitney U test.
Conclusion.
The number of mast cells showed an increased value in oral lichen planus when compared to oral lichenoid reaction and thus an estimation of mast cells count could aid in distinguishing OLP from OLR histopathologically.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Suganya, Ramalingam& Narasimhan, Malathi& Thamizhchelvan, Harikrishnan& Sangeetha, Narasimhan& Rajan, Sharada T. 2018. Role of Mast Cells in Oral Lichen Planus and Oral Lichenoid Reactions. Autoimmune Diseases،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1117620
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Suganya, Ramalingam…[et al.]. Role of Mast Cells in Oral Lichen Planus and Oral Lichenoid Reactions. Autoimmune Diseases No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1117620
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Suganya, Ramalingam& Narasimhan, Malathi& Thamizhchelvan, Harikrishnan& Sangeetha, Narasimhan& Rajan, Sharada T. Role of Mast Cells in Oral Lichen Planus and Oral Lichenoid Reactions. Autoimmune Diseases. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1117620
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1117620
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر