![](/images/graphics-bg.png)
Use of Serotonergic Drugs in Canada for Gastrointestinal Motility Disorders: Results of a Retrospective Cohort Study
المؤلفون المشاركون
Kidane, Biniam
Manji, Farouq
Lam, Jennifer
Taylor, Brian M.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-30
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Surgery for GI dysmotility is limited to those with severe refractory disease.
Though effective, use of serotonergic promotility drugs has been restricted in Canada due to adverse events.
We aimed to investigate utilization of promotility serotonergic drugs in patients under consideration for surgical management.
Methods.
A retrospective cohort study was conducted using prospectively collected data.
The study population included consecutive patients referred to a motility clinic for consideration of bowel resection at a Canadian tertiary hospital (1996–2011).
Univariable tests and multivariable logistic regression analyses were used to assess predictors of serotonergic drug use.
Results.
Of 128 patients, the majority ( n = 98 , 76.6%) had constipation-dominant symptoms.
Only 25% ( n = 32 ) had tried serotonergic promotility drugs.
There was no association between use of these drugs and severity of constipation nor was there an association between serotonergic drug use and presence of diffuse dysmotility (all p > 0.05 ).
The majority of patients ( n = 97 , 75.8%) underwent some type of surgical resection, which was associated with considerable morbidity ( n = 13 , 13.4%).
Conclusions.
Surgical management of GI dysmotility results in serious morbidity.
Serotonergic promotility drugs may allow patients to avoid surgery but disease severity does not predict use of these drugs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kidane, Biniam& Manji, Farouq& Lam, Jennifer& Taylor, Brian M.. 2016. Use of Serotonergic Drugs in Canada for Gastrointestinal Motility Disorders: Results of a Retrospective Cohort Study. Scientifica،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1117781
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kidane, Biniam…[et al.]. Use of Serotonergic Drugs in Canada for Gastrointestinal Motility Disorders: Results of a Retrospective Cohort Study. Scientifica No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1117781
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kidane, Biniam& Manji, Farouq& Lam, Jennifer& Taylor, Brian M.. Use of Serotonergic Drugs in Canada for Gastrointestinal Motility Disorders: Results of a Retrospective Cohort Study. Scientifica. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1117781
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1117781
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)