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Differential Diagnosis of Autoimmune Encephalitis from Infectious Lymphocytic Encephalitis by Analysing the Lymphocyte Subsets of Cerebrospinal Fluid
المؤلفون المشاركون
Zhang, Qiao-quan
Zhang, Yan-fang
Yu, Nian
Lin, Xing-jian
Di, Qing
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
This study is aimed at investigating the lymphocyte subsets of cerebrospinal fluid (CSF) to provide possible differential diagnostic values and better understand the pathophysiological mechanism underlying autoimmune encephalitis (AE) and infectious lymphocytic encephalitis.
A series of CD markers, including CD3/4/8/20 representing different types and developmental stages of lymphocytes, were used to count the corresponding subpopulations of CSF from clinical and laboratory confirmed cases of anti-N-methyl-D-aspartate receptor AE (NMDAR-AE), herpes simplex virus encephalitis (HSVE), and tuberculous meningitis (TBM).
The percentages of lymphocytes observed and the CD4 : CD8 ratios were compared between the three groups.
There were no significant differences of the percentage of total lymphocytes, CD3 cells, and CD4 cells of CSF among each group.
However, there were strongly statistical differences of the CD4 : CD8 ratio in CSF of each group with 0.6 : 1 in NMDAR-AE, 0.9 : 1 in HSVE, and 3.2 : 1 in TBM.
The percentage of CD20 B lymphocytes in NMDAR-AE was statistically higher than that of other groups.
The distinct percentages of lymphocyte subpopulations of CSF appeared to be characteristic and could potentially serve as diagnostic indicators.
Further verification and research will be necessary to clarify the significance and nature of CD4 : CD8 ratios and B lymphocytes in CSF between AE and the infectious lymphocytic encephalitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Qiao-quan& Zhang, Yan-fang& Yu, Nian& Lin, Xing-jian& Di, Qing. 2019. Differential Diagnosis of Autoimmune Encephalitis from Infectious Lymphocytic Encephalitis by Analysing the Lymphocyte Subsets of Cerebrospinal Fluid. Analytical Cellular Pathology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1117912
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Qiao-quan…[et al.]. Differential Diagnosis of Autoimmune Encephalitis from Infectious Lymphocytic Encephalitis by Analysing the Lymphocyte Subsets of Cerebrospinal Fluid. Analytical Cellular Pathology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1117912
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Qiao-quan& Zhang, Yan-fang& Yu, Nian& Lin, Xing-jian& Di, Qing. Differential Diagnosis of Autoimmune Encephalitis from Infectious Lymphocytic Encephalitis by Analysing the Lymphocyte Subsets of Cerebrospinal Fluid. Analytical Cellular Pathology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1117912
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1117912
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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