Study of Frequency and Characteristics of Red Blood Cell Alloimmunization in Thalassemic Patients: Multicenter Study from Palestine
المؤلفون المشاركون
Abu Taha, Adham
Yaseen, Ahmad
Suleiman, Sa’d
Abu Zenah, Omar
Ali, Hammam
Abu Seir, Rania
Younis, Khaled
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-12
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
β-Thalassemia is a common inherited hemolytic disorder in Palestine.
Red blood cell (RBC) transfusion is the principal treatment but it may cause RBC alloimmunization.
This study was conducted to determine the prevalence and characteristics of RBC alloimmunization among thalassemic patients in northern governorates of Palestine.
Methods.
A prospective multicenter observational study was conducted in the thalassemia transfusion centers in the northern governorates of Palestine.
The study included 215 thalassemia patients who received regular blood transfusions.
Clinical and transfusion records of patients were examined.
Antibody screening and identification was conducted using the microcolum gel technique.
Results.
Two hundred fifteen patients were included in the study.
More than half (52.1%) of the patients were males.
The median age of patients was 18 years (range: 12–24 years).
The most frequent blood group was A (40.5%).
Alloantibodies were detected in 12.6% of patients.
Anti-D (33.3%), anti-K (25.9%) and anti-E (14.8%) were the most commonly isolated antibodies.
There was no association between age, sex, starting age of transfusion, number of transfused units, history of splenectomy and alloimmunization.
Conclusions.
Anti-Rh and anti-K antibodies were common among this cohort of patients.
Age, sex, starting age of transfusion, number of transfused units, and history of splenectomy could not predict the occurrence of alloimmunization.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abu Taha, Adham& Yaseen, Ahmad& Suleiman, Sa’d& Abu Zenah, Omar& Ali, Hammam& Abu Seir, Rania…[et al.]. 2019. Study of Frequency and Characteristics of Red Blood Cell Alloimmunization in Thalassemic Patients: Multicenter Study from Palestine. Advances in Hematology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1118084
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abu Taha, Adham…[et al.]. Study of Frequency and Characteristics of Red Blood Cell Alloimmunization in Thalassemic Patients: Multicenter Study from Palestine. Advances in Hematology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1118084
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abu Taha, Adham& Yaseen, Ahmad& Suleiman, Sa’d& Abu Zenah, Omar& Ali, Hammam& Abu Seir, Rania…[et al.]. Study of Frequency and Characteristics of Red Blood Cell Alloimmunization in Thalassemic Patients: Multicenter Study from Palestine. Advances in Hematology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1118084
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1118084
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر