![](/images/graphics-bg.png)
Real-World Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Medical Record Review in France
المؤلفون المشاركون
Davis, Keith L.
Kaye, James A.
Lin, Huamao Mark
Luptakova, Katarina
Nagar, Saurabh P.
Mohty, Mohamad
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-29
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background.
Limited data are available from real-world practices in Europe describing prevailing treatment patterns and outcomes in relapsed/refractory multiple myeloma (RRMM), particularly by cytogenetic risk.
Methods.
A retrospective medical record review was conducted in 200 RRMM patients in France.
From first relapse, patients were assessed on second-/third-line treatments, progression-free survival (PFS), overall survival (OS), and healthcare utilization.
Results.
Fifty-five high risk and 113 standard risk patients were identified.
Overall, 192 patients (96%) received second-line therapy after relapse.
Lenalidomide-based regimens were most common (>50%) in second line.
Hospitalization incidence in high risk patients was approximately twice that of standard risk patients.
From Kaplan-Meier estimation, median (95% CI) second-line PFS was 21.4 (17.5, 25.0) months (by high versus standard risk: 10.6 [6.4, 17.0] versus 28.7 [22.1, 37.3] months).
Among second-line recipients, 47.4% were deceased at data collection.
Median second-line OS was 59.4 (38.8, NE) months (by high versus standard risk: 36.5 [17.4, 50.6] versus 73.6 [66.5, NE] months).
Conclusions.
The prognostic importance of cytogenetic risk in RRMM was apparent, whereby high (versus standard) risk patients had decidedly shorter PFS and OS.
Frequent hospitalizations indicated potentially high costs associated with RRMM, particularly for high risk patients.
These findings may inform economic evaluations of RRMM therapies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lin, Huamao Mark& Davis, Keith L.& Kaye, James A.& Luptakova, Katarina& Nagar, Saurabh P.& Mohty, Mohamad. 2019. Real-World Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Medical Record Review in France. Advances in Hematology،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1118096
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lin, Huamao Mark…[et al.]. Real-World Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Medical Record Review in France. Advances in Hematology No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1118096
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lin, Huamao Mark& Davis, Keith L.& Kaye, James A.& Luptakova, Katarina& Nagar, Saurabh P.& Mohty, Mohamad. Real-World Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Medical Record Review in France. Advances in Hematology. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1118096
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1118096
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)