![](/images/graphics-bg.png)
Basal Insulin Dose in Adults with Type 1 Diabetes Mellitus on Insulin Pumps in Real-Life Clinical Practice: A Single-Center Experience
المؤلفون المشاركون
Klupa, Tomasz
Matejko, Bartlomiej
Malecki, Maciej T.
Kiec-Wilk, Beata
Kukułka, Aneta
Stąpór, Agnieszka
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-05
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction.
Basal insulin (BI) infusion in pump therapy of type 1 diabetes (T1DM) mimics physiological secretion during the night and between meals.
The recommended percentage of the total BI to daily insulin dose (termed the %BI) ranges between 30 and 50%.
We analyzed whether this recommendation was followed in adults with T1DM from a university center, and whether BI doses were linked with glycemic control.
Materials and Methods.
We included 260 consecutive patients with T1DM (159 women and 101 men) treated with continuous subcutaneous insulin infusion at the Department of Metabolic Diseases, Krakow, Poland.
Data were downloaded from patients’ pumps and collected from medical records.
We analyzed the settings of BI and the association of %BI with HbA1c level.
Linear regression was performed.
Results.
The mean age of T1DM individuals was 26.6 ± 8.2 years, BMI was 23.1 ± 3.0 kg/m2, T1DM duration was 13.3 ± 6.4 years, and HbA1c level was 7.4%.
There were 69.6% (n=181) of T1DM patients with %BI in the recommended range.
The T1DM duration and HbA1c level of patients with a %BI <30% (n=23) was 9.5 years and 6.4%, respectively; for a %BI of 30–50%, it was 13.2 years and 7.4%; and for a %BI >50% (n=56), it was 15.8 years and 7.8% (p<0.001 for both three-group comparisons).
Multiple regression identified %BI among independent predictors of the HbA1c level.
Conclusion.
In this real-life analysis, the recommendations concerning %BI dosing were not followed by almost one-third of adult T1DM patients.
Low %BI was associated with better glycemic control; however, this requires further confirmation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Matejko, Bartlomiej& Kukułka, Aneta& Kiec-Wilk, Beata& Stąpór, Agnieszka& Klupa, Tomasz& Malecki, Maciej T.. 2018. Basal Insulin Dose in Adults with Type 1 Diabetes Mellitus on Insulin Pumps in Real-Life Clinical Practice: A Single-Center Experience. Advances in Medicine،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1118505
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Matejko, Bartlomiej…[et al.]. Basal Insulin Dose in Adults with Type 1 Diabetes Mellitus on Insulin Pumps in Real-Life Clinical Practice: A Single-Center Experience. Advances in Medicine No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1118505
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Matejko, Bartlomiej& Kukułka, Aneta& Kiec-Wilk, Beata& Stąpór, Agnieszka& Klupa, Tomasz& Malecki, Maciej T.. Basal Insulin Dose in Adults with Type 1 Diabetes Mellitus on Insulin Pumps in Real-Life Clinical Practice: A Single-Center Experience. Advances in Medicine. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1118505
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1118505
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)