Increased Whole Blood Viscosity Is Associated with the Presence of Digital Ulcers in Systemic Sclerosis: Results from a Cross-Sectional Pilot Study
المؤلفون المشاركون
Korsten, Peter
Zeisberg, Michael
Cho, Daniel
Zachary, Lawrence S.
Volkov, Suncica
Sweiss, Nadera J.
Niewold, Timothy B.
Utset, Tammy O.
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-29
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the role of whole blood viscosity in digital ulcer (DU) development in patients with diffuse and limited Systemic sclerosis.
Methods.
A convenience sample of patients with Systemic sclerosis (SSc) was selected from the adult Rheumatology clinic at the University of Chicago.
The study group consisted of patients with SSc (with ulcers present, a history of ulcers, and no ulcers); the control group consisted of matched healthy Rheumatology clinic staff.
WBV was measured using a scanning capillary viscometer at different shear rates (1–1000 1/s).
Results.
Whole blood viscosity as measured by a scanning capillary viscometer was increased in patients with SSc compared to healthy controls (p<0.0001).
Additionally, patients with present DU had significantly higher whole blood viscosity when compared to patients with a history of DU and patients with no history of DU (p<0.0001).
These findings were most pronounced at lower shear rates between 1 and 10 1/s.
Conclusion.
Whole blood viscosity might be a contributing factor in DU development in patients with SSc.
Further studies with larger patient cohorts are required to fully evaluate how increased WBV contributes to the development of DU and whether the currently available treatment options improve the microcirculation by influencing WBV.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Korsten, Peter& Niewold, Timothy B.& Zeisberg, Michael& Utset, Tammy O.& Cho, Daniel& Zachary, Lawrence S.…[et al.]. 2017. Increased Whole Blood Viscosity Is Associated with the Presence of Digital Ulcers in Systemic Sclerosis: Results from a Cross-Sectional Pilot Study. Autoimmune Diseases،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1121749
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Korsten, Peter…[et al.]. Increased Whole Blood Viscosity Is Associated with the Presence of Digital Ulcers in Systemic Sclerosis: Results from a Cross-Sectional Pilot Study. Autoimmune Diseases No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1121749
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Korsten, Peter& Niewold, Timothy B.& Zeisberg, Michael& Utset, Tammy O.& Cho, Daniel& Zachary, Lawrence S.…[et al.]. Increased Whole Blood Viscosity Is Associated with the Presence of Digital Ulcers in Systemic Sclerosis: Results from a Cross-Sectional Pilot Study. Autoimmune Diseases. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1121749
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1121749
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر