![](/images/graphics-bg.png)
Association of Endothelial Function with Parental Hypertension in Normotensive-Obese African-American Women: A Pilot Study
المؤلفون المشاركون
Bond, Vernon
Becknel, Karissa
Dorsey, James
Gorantla, Vasavi R.
Volkova, Yulia A.
Kumar, Krishna
Millis, Richard M.
المصدر
Advances in Preventive Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-03
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Obese African-American (AA) women are at high risk of hypertension (HT) and cardiovascular disease (CVD).
Flow-mediated dilation (FMD) and arterial augmentation index (AI) are measures of endothelial function and arterial stiffness.
Whether endothelial function and arterial stiffness predict risk of HT or CVD in obese African-American women with, versus without, parental histories of HT and whether aerobic exercise is an effective countermeasure remain unclear.
The capacity for FMD is partly heritable.
Therefore, we tested the hypotheses that less FMD and greater AI may be found in normotensive-obese, young-adult (18-26 year-old) AA women with hypertensive parents (n=10) than in a matched control group with normotensive parents (n=10) and that a single bout of aerobic exercise improves both endothelial function and arterial stiffness, with less improvement in the women with hypertensive parents.
We studied each subject while at rest, 20 min before and 20 min after, 30 min of aerobic exercise.
The exercise-induced changes and parental hypertension-related differences in AI were not significant.
The exercise increased FMD in both of the groups with no significant difference in magnitude between the women with hypertensive and normotensive parents.
FMD was significantly less in the women with hypertensive parents than in the women with normotensive parents after, but not before, the exercise (mean ±95% confidence interval of 11.3 ± 4.9% vs.
15.6 ± 4.9%, P=0.05).
These findings suggest that a 30-min bout of aerobic exercise may improve FMD and unmask endothelial dysfunction in normotensive-obese, young-adult AA women with parental histories of HT.
Future studies should determine whether regular aerobic exercise protects obese AA women from the endothelial dysfunction associated with diabetes and prevents CVD in this high-risk population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bond, Vernon& Becknel, Karissa& Kumar, Krishna& Dorsey, James& Gorantla, Vasavi R.& Volkova, Yulia A.…[et al.]. 2019. Association of Endothelial Function with Parental Hypertension in Normotensive-Obese African-American Women: A Pilot Study. Advances in Preventive Medicine،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1121809
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bond, Vernon…[et al.]. Association of Endothelial Function with Parental Hypertension in Normotensive-Obese African-American Women: A Pilot Study. Advances in Preventive Medicine No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1121809
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bond, Vernon& Becknel, Karissa& Kumar, Krishna& Dorsey, James& Gorantla, Vasavi R.& Volkova, Yulia A.…[et al.]. Association of Endothelial Function with Parental Hypertension in Normotensive-Obese African-American Women: A Pilot Study. Advances in Preventive Medicine. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1121809
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1121809
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)