Zirconium (IV)‎ Acetylacetonate: Ring-Opening Initiator Mediating One-Step Synthesis of Biodegradable Polyacids

الملخص EN

Biodegradable polyacid is obtained in one-step ring-opening polymerization (ROP) of carboxylic-acid-functionalized six-membered cyclic carbonate mediated with zirconium (IV) acetylacetonate.

Exemplary copolymers with L,L-lactide are described as well.

Moreover, zirconium (IV) acetylacetonate is found to be active catalyst of trimethylene carbonate (TMC) ROP in presence of carboxylic acid yielding PTMC end-capped with the acid derivative.

Polymerization mechanism is hypothesized demonstrating possibilities of the method in work-saving polycation synthesis and one-step method of conjugate synthesis of well-known biocompatible polyesters and polycarbonates.