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Characterization of the Biological Fingerprint and Identification of Associated Parameters in Stress Fractures by FTIR Spectroscopy
المؤلفون المشاركون
Vazquez-Zapien, Gustavo Jesus
Mata-Miranda, Monica Maribel
Guerrero-Ruiz, Melissa
Gonzalez-Fuentes, Juan Ramon
Hernandez-Toscano, Carlos Martin
Garcia-Andino, Jesus Rafael
Sanchez-Brito, Miguel
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-22
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Introduction.
The stress fractures (SFs) are a common condition in athletes and military recruits, characterized by partial fracture caused by repetitive applications of stresses that are lower than the stress required to fracture the bone in a single loading.
Fourier transform infrared (FTIR) spectroscopy gives information about the bone composition and also can determine the amount of a molecule.
For this reason, the FTIR spectroscopy may be used as a tool for diagnosis of certain bone diseases related to the bone strength.
In this research, we established the contributions of mineral and collagen properties to SF risk through FTIR spectroscopy, analyzing the biochemical profile differences between the healthy bone and the bone with an SF.
Materials and Methods.
Previous written informed consent was obtained, and samples of the hip with an SF (n = 11) and healthy bone from the femur with traumatic fracture (n = 5) were obtained and analyzed employing FTIR spectroscopy and its biochemical mapping function.
Then, using FTIR spectra and the map, the collagen content and ratios corresponding to matrix maturity, mineralization, carbonate substitution, acid phosphate substitution, and crystallinity were calculated.
Moreover, a histopathological analysis through Masson’s staining was conducted.
Results.
The biochemical analysis showed that the bone with an SF presented a bone immaturity characterized by a higher content of collagen, lower matrix maturity, mineralization, carbonate and acid phosphate substitutions, and greater crystallinity compared to the healthy bone, being checked by the ratio analysis and biochemical mapping.
Besides, Masson’s stain showed a higher collagen content in the bone with an SF.
Conclusions.
The bone with an SF presented alterations in its biochemical composition, showing bone immaturity, which broadens the panorama of the condition to investigate future treatments or prophylactic techniques.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mata-Miranda, Monica Maribel& Guerrero-Ruiz, Melissa& Gonzalez-Fuentes, Juan Ramon& Hernandez-Toscano, Carlos Martin& Garcia-Andino, Jesus Rafael& Sanchez-Brito, Miguel…[et al.]. 2019. Characterization of the Biological Fingerprint and Identification of Associated Parameters in Stress Fractures by FTIR Spectroscopy. BioMed Research International،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1123210
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mata-Miranda, Monica Maribel…[et al.]. Characterization of the Biological Fingerprint and Identification of Associated Parameters in Stress Fractures by FTIR Spectroscopy. BioMed Research International No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1123210
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mata-Miranda, Monica Maribel& Guerrero-Ruiz, Melissa& Gonzalez-Fuentes, Juan Ramon& Hernandez-Toscano, Carlos Martin& Garcia-Andino, Jesus Rafael& Sanchez-Brito, Miguel…[et al.]. Characterization of the Biological Fingerprint and Identification of Associated Parameters in Stress Fractures by FTIR Spectroscopy. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1123210
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1123210
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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