Maternal Body Mass Index and Risk of Congenital Heart Defects in Infants: A Dose-Response Meta-Analysis
المؤلفون المشاركون
Liu, Xuezhen
Ding, Guoyong
Yang, Weili
Feng, Xia
Li, Yuejin
Liu, Huamin
Zhang, Qianqian
Ji, Long
Li, Dong
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-07-07
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Objective.
The exact shape of the dose-response relationship between maternal body mass index (BMI) and the risk of congenital heart defects (CHDs) in infants has not been clearly defined yet.
This study aims to further clarify the relationship between maternal obesity and the risk of CHDs in infants by an overall and dose-response meta-analysis.
Methods.
PubMed, Embase, and Web of Science databases were searched to identify all related studies.
The studies were limited to human cohort or case-control studies in English language.
Random-effect models and dose-response meta-analysis were used to synthesize the results.
Heterogeneity, subgroup analysis, sensitivity analysis, and publication bias were also assessed.
Results.
Nineteen studies with 2,416,546 participants were included in our meta-analysis.
Compared with the mothers with normal weight, the pooled relative risks (RRs) of infants with CHDs were 1.08 (95% CI=1.03-1.13) in overweight and 1.23 (95% CI=1.17-1.29) in obese mothers.
According to the findings from the linear meta-analysis, we observed an increased risk of infants with CHDs (RR=1.07, 95% CI=1.06-1.08) for each 5 kg/m2 increase in maternal BMI.
A nonlinear relationship between maternal BMI and risk of infants with CHDs was also found (p=0.012).
Conclusion.
The results from our meta-analysis indicate that increased maternal BMI is related to increased risk of CHDs in infants.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Xuezhen& Ding, Guoyong& Yang, Weili& Feng, Xia& Li, Yuejin& Liu, Huamin…[et al.]. 2019. Maternal Body Mass Index and Risk of Congenital Heart Defects in Infants: A Dose-Response Meta-Analysis. BioMed Research International،Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1123269
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Xuezhen…[et al.]. Maternal Body Mass Index and Risk of Congenital Heart Defects in Infants: A Dose-Response Meta-Analysis. BioMed Research International No. 2019 (2019), pp.1-14.
https://search.emarefa.net/detail/BIM-1123269
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Xuezhen& Ding, Guoyong& Yang, Weili& Feng, Xia& Li, Yuejin& Liu, Huamin…[et al.]. Maternal Body Mass Index and Risk of Congenital Heart Defects in Infants: A Dose-Response Meta-Analysis. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1123269
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1123269
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر