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C-Reactive Protein Levels at the Midpregnancy Can Predict Gestational Complications
المؤلفون المشاركون
Dallegri, Franco
Montecucco, Fabrizio
Carbone, Federico
Cordera, Renzo
Bonaventura, Aldo
Vecchié, Alessandra
Maggi, Davide
Ferraiolo, Antonella
Carloni, Beatrice
Andraghetti, Gabriella
Affinito Bonabello, Laura
Liberale, Luca
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Although essential for a successful pregnancy, a growing body of evidence suggests that maternal inflammation, when dysregulated, may represent a risk factor for both maternal and neonatal outcomes.
Here, we assessed the accuracy of maternal C-reactive protein (CRP) concentrations at the middle phase of pregnancy in the identification of maternal adverse outcomes (MAO) until delivery.
A correlation between CRP and a complicated pregnancy including both maternal and neonatal adverse outcomes has been investigated, too.
In this retrospective study, conducted at the Diabetology Unit of IRCCS Ospedale Policlinico San Martino, Genoa (Italy), 380 outpatient pregnant women have been enrolled at the prenatal visit before performing a 75 g oral glucose tolerance test at 24th-26th gestational week for gestational diabetes mellitus (GDM) screening.
Demographic, medical, and reproductive history has been obtained by verbal interview.
Data about pregnancy and delivery have been retrieved from medical records.
The median value of maternal baseline serum CRP was 3.25 μg/mL.
Women experiencing MAO were older, more frequently suffering from hypertension, and showed higher CRP concentrations, with a cutoff value >1.86 μg/mL found by a ROC curve analysis to be accurately predictive for MAO.
By a logistic regression analysis, serum CRP levels >1.86 μg/mL have been found to predict MAO also considering maternal age, hypertension, and GDM.
Maternal CRP levels have been positively associated with overall pregnancy adverse outcomes (maternal and neonatal), too.
In conclusion, in pregnant women serum levels of CRP can early recognize subjects at higher risk for maternal and neonatal complications needing a more stringent follow-up.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vecchié, Alessandra& Bonaventura, Aldo& Carbone, Federico& Maggi, Davide& Ferraiolo, Antonella& Carloni, Beatrice…[et al.]. 2018. C-Reactive Protein Levels at the Midpregnancy Can Predict Gestational Complications. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1124138
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vecchié, Alessandra…[et al.]. C-Reactive Protein Levels at the Midpregnancy Can Predict Gestational Complications. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1124138
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vecchié, Alessandra& Bonaventura, Aldo& Carbone, Federico& Maggi, Davide& Ferraiolo, Antonella& Carloni, Beatrice…[et al.]. C-Reactive Protein Levels at the Midpregnancy Can Predict Gestational Complications. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1124138
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1124138
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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