Changes in Lipid Indices in HIV+ Cases on HAART
المؤلفون المشاركون
Ji, Shujing
Brockmeyer, Norbert H.
Xu, Yufan
Han, Dating
Peng, Xiuming
Wu, Nanping
Lu, Xiangyun
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-05
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
We assess long-term changes in lipid levels in human immunodeficiency disease- (HIV-) infected patients undergoing highly active antiretroviral treatment (HAART) and their association with diabetes mellitus (DM) and thyroid dysfunction.
We observed changes in the levels of total cholesterol (TC) and total triglyceride (TG) of 63 HIV-infected patients in the 6 years from starting HAART and analyzed correlations between relevant parameters.
TC levels of patients with normal baseline TC levels as well as those diagnosed with DM or impaired fasting glucose (IFG) increased significantly (P < 0.05) as did the TG levels of patients with normal baseline TG levels (P < 0.05).
TC levels of patients with hypercholesterolemia in the year HAART was initiated were significantly higher than those of patients with normal baseline TC levels (P < 0.05) for all 6 years.
TC levels of patients diagnosed with DM were significantly higher than those with euglycemia (P < 0.05) 2 and 4 years after HAART commencement.
Levels of TC, high-density lipoprotein-cholesterol (HDL-C), and low-density lipoprotein-cholesterol (LDL-C) were correlated negatively with viral load, whereas levels of TC and very-low-density lipoprotein-cholesterol (VLDL-C) were correlated positively with CD4+ cell counts before HAART commencement.
Linear mixed-effect model demonstrated disturbance of glucose metabolism and HAART containing nevirapine and CD4+ cell count were positively correlated with TC levels after HAART commencement.
These findings suggest that there are changes in the lipid levels of patients undergoing HAART, with the potential risk of dyslipidemia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ji, Shujing& Xu, Yufan& Han, Dating& Peng, Xiuming& Lu, Xiangyun& Brockmeyer, Norbert H.…[et al.]. 2019. Changes in Lipid Indices in HIV+ Cases on HAART. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1124150
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ji, Shujing…[et al.]. Changes in Lipid Indices in HIV+ Cases on HAART. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1124150
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ji, Shujing& Xu, Yufan& Han, Dating& Peng, Xiuming& Lu, Xiangyun& Brockmeyer, Norbert H.…[et al.]. Changes in Lipid Indices in HIV+ Cases on HAART. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1124150
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1124150
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر