Heart Failure Duration Combined with Left Atrial Dimension Predicts Super-Response and Long-Term Prognosis in Patients with Cardiac Resynchronization Therapy Implantation
المؤلفون المشاركون
Wang, Jiang
Guo, Zhinian
Liu, Xiaoyan
Liu, Chuan
Yang, Jie
Cheng, Xiaofeng
Chen, Yunlong
Li, Ping
He, Yongming
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-06-24
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Response to cardiac resynchronization therapy (CRT) varies significantly among patients.
This study aimed to identify baseline characteristics that could predict super-response to CRT and to evaluate the long-term prognosis in super-responders.
Methods.
We retrospectively reviewed the data of 73 consecutive patients who received CRT.
Patients were considered as super-responders after 6-month follow-up when NYHA class reduction to I or II combined with left ventricular ejection fraction (LVEF) ≥ 50% was observed.
Patients were divided into super-responders group and non-super-responders group.
All-cause mortality or hospitalization for heart failure (HF) was referred to the combined end point.
Results.
17 (23.3%) patients were super-responders.
HF duration, left atrial dimension (LAD), and left bundle branch block (LBBB) were independent predictors of super-response to CRT.
The combination of HF duration and LAD could provide more robust prediction of super-response than standalone HF duration (0.899 versus 0.789, Z = 2.207, P = 0.027) or standalone LAD (0.899 versus 0.775, Z = 2.487, P = 0.013).
super-responders had excellent LV reverse remodeling.
The cumulative incidences of combined end point were significantly lower in the super-responders group, LAD ≤ 42mm group, and combination of HF duration ≤ 48 months and LAD ≤ 42mm group.
LBBB remained associated with a lowered risk of the combined end point (HR: 0.19, 95% CI: 0.07-0.57, P = 0.003), whereas LAD was associated with a raised risk of the combined end point (HR: 1.09, 95% CI: 1.02-1.17, P = 0.014).
Conclusions.
HF duration, LAD, and LBBB independently predicted super-response.
The combination of HF duration and LAD makes more robust prediction of CRT super-response.
Super-responders had excellent LV reverse remodeling and decreased the incidences of the combined end point.
LBBB and LAD were independently associated with the combined end point.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Guo, Zhinian& Liu, Xiaoyan& Liu, Chuan& Yang, Jie& Cheng, Xiaofeng& Chen, Yunlong…[et al.]. 2019. Heart Failure Duration Combined with Left Atrial Dimension Predicts Super-Response and Long-Term Prognosis in Patients with Cardiac Resynchronization Therapy Implantation. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1124253
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Guo, Zhinian…[et al.]. Heart Failure Duration Combined with Left Atrial Dimension Predicts Super-Response and Long-Term Prognosis in Patients with Cardiac Resynchronization Therapy Implantation. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1124253
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Guo, Zhinian& Liu, Xiaoyan& Liu, Chuan& Yang, Jie& Cheng, Xiaofeng& Chen, Yunlong…[et al.]. Heart Failure Duration Combined with Left Atrial Dimension Predicts Super-Response and Long-Term Prognosis in Patients with Cardiac Resynchronization Therapy Implantation. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1124253
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1124253
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر