Prebiotic Effect of Lycopene and Dark Chocolate on Gut Microbiome with Systemic Changes in Liver Metabolism, Skeletal Muscles and Skin in Moderately Obese Persons
المؤلفون المشاركون
Klochkov, Victor A.
Nielsen, D. S.
Bashmakov, Yuriy K.
Krych, Łukasz
Chalyk, Natalia E.
Chernyshova, Marina P.
Pristensky, Dmitry V.
Wiese, Maria
Kot, Witold
Bandaletova, Tatyana
Petyaev, Ivan M.
Kyle, Nigel
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-06-02
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Lycopene rich food and dark chocolate are among the best-documented products with a broad health benefit.
This study explored the systemic effect of lycopene and dark chocolate (DC) on gut microbiota, blood, liver metabolism, skeletal muscle tissue oxygenation and skin.
30 volunteers were recruited for this trial, 15 women and 15 men with a mean age of 55 ± 5.7 years and with moderate obesity, 30 < BMI < 35 kg/m2.
They were randomized and divided into five equal interventional groups: three received different formulations of lycopene, one of them with a 7 mg daily dose and two with 30 mg; another group was given 10 g of DC with 7 mg lycopene embedded into its matrix, and the last group received 10 g DC.
The trial was double-blinded for the three lycopene groups and separately for the 2 DC groups; the trial lasted for 1 month.
By the end of the trial there were dose-dependent changes in the gut microbiota profile in all three lycopene groups with an increase of relative abundance of, e.g., Bifidobacterium adolescentis and Bifidobacterium longum.
This was also accompanied by dose-dependent changes in the blood, liver metabolism, skeletal muscle and skin parameters.
Consumption of DC resulted in increased relative abundance of, e.g., Lactobacillus and a reduction of corneocyte exfoliation.
This is the first study which reports the prebiotic potential of lycopene and DC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wiese, Maria& Bashmakov, Yuriy K.& Chalyk, Natalia E.& Nielsen, D. S.& Krych, Łukasz& Kot, Witold…[et al.]. 2019. Prebiotic Effect of Lycopene and Dark Chocolate on Gut Microbiome with Systemic Changes in Liver Metabolism, Skeletal Muscles and Skin in Moderately Obese Persons. BioMed Research International،Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1125464
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wiese, Maria…[et al.]. Prebiotic Effect of Lycopene and Dark Chocolate on Gut Microbiome with Systemic Changes in Liver Metabolism, Skeletal Muscles and Skin in Moderately Obese Persons. BioMed Research International No. 2019 (2019), pp.1-15.
https://search.emarefa.net/detail/BIM-1125464
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wiese, Maria& Bashmakov, Yuriy K.& Chalyk, Natalia E.& Nielsen, D. S.& Krych, Łukasz& Kot, Witold…[et al.]. Prebiotic Effect of Lycopene and Dark Chocolate on Gut Microbiome with Systemic Changes in Liver Metabolism, Skeletal Muscles and Skin in Moderately Obese Persons. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1125464
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1125464
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر