Assessment of Changes in Lipids Metabolism in Patients with Degenerative Joints and Discs Diseases Subjected to Spa Therapy

الملخص EN

Introduction.

High levels of total cholesterol, triglycerides, and, connected with them, lipoprotein fractions may result in atherosclerosis.

There are various forms of therapy used to prevent cardiovascular diseases, such as balneophysiotherapy, the effectiveness of which is confirmed by numerous scientific publications.

Objective.

The objective of this study was to assess the impact of balneophysiotherapeutic procedures on the systemic metabolism of lipids in patients suffering from osteoarthritis of the motor organ.

Material and Methods.

The study was conducted in the Health Resort Świeradów-Zdrój.

Observation included patients undergoing radon water therapy.

Before therapy and after 21 days of treatment, lipid profile was assessed with the use of standard colorimetric assay.

Study group consisted of n=34 patients with degenerative joints and disc disease.

The mean age of patients was 56.5l.

The control group consisted of 17 people selected among the employees of the spa also suffering from osteoarthritis.

The mean age was 54.2 years.

Results.

The results of the study are based on a single, 21-day health resort stay period in April/May.

A statistically significant increase in HDL cholesterol levels was observed in female patients having undergone health resort treatment (P<0.01).

Statistically significant drops in LDL cholesterol and TG levels were observed in the control group (P<0.01).

An increase in HDL levels was observed in the male and female control subjects, with P<0.05.

Conclusions.

(1) After the end of therapy, there were no changes in lipid metabolism in men, while in the group of women an increase in HDL level was observed.

(2) In the control group, statistically significant changes in the field of lipid metabolism may be related to lifestyle changes as a result of educational activities conducted prior to the research.

(3) Due to the divergent results, it is advisable to conduct randomized studies in a larger population.

This trial is registered with NCT03274128.