GAAP: A Genome Assembly + Annotation Pipeline
المؤلفون المشاركون
Kong, Jinhwa
Huh, Sun
Won, Jung-Im
Yoon, Jeehee
Kim, Baeksop
Kim, Kiyong
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-06-26
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Genomic analysis begins with de novo assembly of short-read fragments in order to reconstruct full-length base sequences without exploiting a reference genome sequence.
Then, in the annotation step, gene locations are identified within the base sequences, and the structures and functions of these genes are determined.
Recently, a wide range of powerful tools have been developed and published for whole-genome analysis, enabling even individual researchers in small laboratories to perform whole-genome analyses on their objects of interest.
However, these analytical tools are generally complex and use diverse algorithms, parameter setting methods, and input formats; thus, it remains difficult for individual researchers to select, utilize, and combine these tools to obtain their final results.
To resolve these issues, we have developed a genome analysis pipeline (GAAP) for semiautomated, iterative, and high-throughput analysis of whole-genome data.
This pipeline is designed to perform read correction, de novo genome (transcriptome) assembly, gene prediction, and functional annotation using a range of proven tools and databases.
We aim to assist non-IT researchers by describing each stage of analysis in detail and discussing current approaches.
We also provide practical advice on how to access and use the bioinformatics tools and databases and how to implement the provided suggestions.
Whole-genome analysis of Toxocara canis is used as case study to show intermediate results at each stage, demonstrating the practicality of the proposed method.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kong, Jinhwa& Huh, Sun& Won, Jung-Im& Yoon, Jeehee& Kim, Baeksop& Kim, Kiyong. 2019. GAAP: A Genome Assembly + Annotation Pipeline. BioMed Research International،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1125584
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kong, Jinhwa…[et al.]. GAAP: A Genome Assembly + Annotation Pipeline. BioMed Research International No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1125584
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kong, Jinhwa& Huh, Sun& Won, Jung-Im& Yoon, Jeehee& Kim, Baeksop& Kim, Kiyong. GAAP: A Genome Assembly + Annotation Pipeline. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1125584
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1125584
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر