Computational Study on the Biomechanics of Pupil Block Phenomenon
المؤلفون المشاركون
Wang, Wenjia
Song, Hongfang
Liu, Zhicheng
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-25
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Pupil blocking force (PBF) can indicate the potential risk of pupil block (PB), which is considered as a main pathogenic factor of primary angle-closure glaucoma (PACG).
However, the effect of PB on the PBF under different pupil diameters and iris-lens channel (ILC) distance was unknown.
Besides, a simple and practical method to assess PBF has not been reported yet.
In this study, 21 finite element models of eyes with various pupil diameters (2.4 mm–2.6 mm) and ILC (2 μm–20 μm) were constructed and were conducted to simulate aqueous humor flow by fluid-solid coupling numerical simulation.
PBF in each model was calculated based on the numerical simulation results and was fitted using response surface methodology.
The results demonstrated that ILC distance had a more significant effect than pupil diameter on PBF.
With the decrease of ILC distance, the PBF increased exponentially.
When the reduced distance was lower than 5 μm, the PBF exploded quickly, resulting in a high risk of iris bomb.
The PBF also varied with pupil diameter, especially under the condition of narrow ILC.
Both ILC distance and pupil diameter could explain more than 97% variation in PBF, and a second-order empirical model has been developed to be a good predictor of PBF.
Based on the linear relationship between anterior chamber deformation and PBF, a threshold value of PBF was given to guide clinical decisions.
This study could be used to investigate PACG pathological correlation and its pathogenesis, so as to provide a reference value for clinical diagnosis of PACG.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Wenjia& Song, Hongfang& Liu, Zhicheng. 2019. Computational Study on the Biomechanics of Pupil Block Phenomenon. BioMed Research International،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1125622
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Wenjia…[et al.]. Computational Study on the Biomechanics of Pupil Block Phenomenon. BioMed Research International No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1125622
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Wenjia& Song, Hongfang& Liu, Zhicheng. Computational Study on the Biomechanics of Pupil Block Phenomenon. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1125622
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1125622
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر