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Immunological and Clinical Characteristics of Systemic Lupus Erythematosus: A Series from Morocco
المؤلفون المشاركون
Barakat, Amina
Ghailani Nourouti, Naima
Bennani Mechita, Mohcine
Zian, Zeineb
Maamar, Mouna
Aouni, Mohamed El
El Aouad, Rajae
Arji, Naima
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-09-30
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease with a high female predominance.
To date, studies about SLE in Morocco are few.
This retrospective study describes the clinical and immunological features in a series of 50 SLE Moroccan patients in University Hospital Center of Rabat, Morocco, between December 2011 and December 2013.
All patients were screened for antinuclear antibodies (ANA) and anti-DNA antibodies by indirect immunofluorescence, followed by identification of anti-extractable nuclear antigen antibodies by ELISA.
The female to male ratio was 6.1:1.
Mean age was 31.72 years.
The main clinical manifestations were arthritis (82%), mucocutaneous manifestations (80%), renal manifestations (50%), and hematological features (46%).
Of the mucocutaneous features, the highest frequencies were observed in the malar rash (68%) and photosensitivity (60%).
Of the hematological features, lymphopenia was most frequently observed in 30% of patients, followed by hemolytic anemia in 16% and leucopenia and thrombocytopenia in 8%.
Central nervous system was involved in 10%.
ANA were found in 88%, anti-DNA antibodies in 56%, and anti-Sm antibodies in 50%.
Anti-SSA, anti-SSB, anti-Sm/RNP, and anti-Scl70 antibodies were detected in 38%, 10%, 48%, and 8%, respectively.
Our data show that, in our patients, the main clinical and immunological features of SLE remain comparable to patients from other Arab countries.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zian, Zeineb& Maamar, Mouna& Aouni, Mohamed El& Barakat, Amina& Ghailani Nourouti, Naima& El Aouad, Rajae…[et al.]. 2018. Immunological and Clinical Characteristics of Systemic Lupus Erythematosus: A Series from Morocco. BioMed Research International،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1125662
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zian, Zeineb…[et al.]. Immunological and Clinical Characteristics of Systemic Lupus Erythematosus: A Series from Morocco. BioMed Research International No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1125662
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zian, Zeineb& Maamar, Mouna& Aouni, Mohamed El& Barakat, Amina& Ghailani Nourouti, Naima& El Aouad, Rajae…[et al.]. Immunological and Clinical Characteristics of Systemic Lupus Erythematosus: A Series from Morocco. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1125662
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1125662
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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