Natural Compounds for the Management of Parkinson’s Disease and Attention-DeficitHyperactivity Disorder
المؤلف
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-22
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Parkinson’s disease (PD) is the second most common neurodegenerative disorder with an unknown aetiology.
The pathogenic mechanisms include oxidative stress, mitochondrial dysfunction, protein dysfunction, inflammation, autophagy, apoptosis, and abnormal deposition of α-synuclein.
Currently, the existing pharmacological treatments for PD cannot improve fundamentally the degenerative process of dopaminergic neurons and have numerous side effects.
On the other hand, attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood and is characterised by hyperactivity, impulsivity, and inattention.
The aetiology of ADHD remains unknown, although it has been suggested that its pathophysiology involves abnormalities in several brain regions, disturbances of the catecholaminergic pathway, and oxidative stress.
Psychostimulants and nonpsychostimulants are the drugs prescribed for the treatment of ADHD; however, they have been associated with increased risk of substance use and have several side effects.
Today, there are very few tools available to prevent or to counteract the progression of such neurological disorders.
Thus, therapeutic approaches with high efficiency and fewer side effects are needed.
This review presents a brief overview of the two neurological disorders and their current treatments, followed by a discussion of the natural compounds which have been studied as therapeutic agents and the mechanisms underlying the beneficial effects, in particular, the decrease in oxidative stress.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Corona, Juan Carlos. 2018. Natural Compounds for the Management of Parkinson’s Disease and Attention-DeficitHyperactivity Disorder. BioMed Research International،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1126319
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Corona, Juan Carlos. Natural Compounds for the Management of Parkinson’s Disease and Attention-DeficitHyperactivity Disorder. BioMed Research International No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1126319
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Corona, Juan Carlos. Natural Compounds for the Management of Parkinson’s Disease and Attention-DeficitHyperactivity Disorder. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1126319
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126319
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر