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An Evaluation of Clinical and Histopathological Aspects of Patients with Oral Submucous Fibrosis in the Background of Oral Squamous Cell Carcinoma
المؤلفون المشاركون
Siriwardena, B. S. M. S.
Jayawardena, K. L. T. D.
Senarath, N. H.
Tilakaratne, W. M.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-09
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The behavior and prognosis of oral squamous cell carcinoma (OSCC) is presumably different in patients with oral submucous fibrosis (OSF).
The objective of this study was to assess the effects of demographic features, habits, and histopathological features in the transformation of OSF to OSCC.
Methods.
Data were extracted from the archives and histopathological evaluation and presence of nodal metastasis were recorded.
Results.
OSF was detected in 130 (48%) out of 273 OSCC patients.
The mean age of presentation among OSF-positive patients was 57.7 years, while patients diagnosed only with OSCC had a comparatively higher age, 59.5 years.
In the below 50 years of age group, presence of OSF with OSCC was less (40%).
In the OSF-positive group, male to female ratio was 3.2:1.
The common primary sites were buccal mucosa and tongue in both groups.
Betel quid chewing was present in more than 95% of the sample.
Betel chewing, smoking, and alcohol consumption were present in 26.15% of OSF-positive patients.
Degree of fibrosis was neither associated with the level of histological differentiation of the tumor (p= 0.195) nor associated with the malignant transformation (p =0.373).
Lymph node metastasis was not seen in 76.63% and 68.54% of the patients with and without OSF, respectively.
Conclusions.
High degree of prevalence of OSF was observed among the OSCC patients.
There were also a male predilection and younger age at presentation in these patients.
However, a significant association was not observed in the degree of fibrosis with malignant transformation or the level of histopathological differentiation of the tumor.
Lymph node metastasis also failed to express a significant relationship with the presence of OSF.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Siriwardena, B. S. M. S.& Jayawardena, K. L. T. D.& Senarath, N. H.& Tilakaratne, W. M.. 2018. An Evaluation of Clinical and Histopathological Aspects of Patients with Oral Submucous Fibrosis in the Background of Oral Squamous Cell Carcinoma. BioMed Research International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1126413
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Siriwardena, B. S. M. S.…[et al.]. An Evaluation of Clinical and Histopathological Aspects of Patients with Oral Submucous Fibrosis in the Background of Oral Squamous Cell Carcinoma. BioMed Research International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1126413
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Siriwardena, B. S. M. S.& Jayawardena, K. L. T. D.& Senarath, N. H.& Tilakaratne, W. M.. An Evaluation of Clinical and Histopathological Aspects of Patients with Oral Submucous Fibrosis in the Background of Oral Squamous Cell Carcinoma. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1126413
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126413
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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