Serological Detection of Rh-Del Phenotype among Rh-Negative Blood Donors at National Blood Center, Yangon, Myanmar
المؤلفون المشاركون
Wah, Saw Thu
Chi, Saung Nay
Kyaing, Kyi Kyi
Khin, Aye Aye
Aung, Thida
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-18
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Red cell Rhesus (Rh) antigen expression is influenced by the genetic polymorphism of RHD and RHCE genes and reveals serologically different reactions of RhD variants such as partial D, weak D, and Rh-Del.
Serologically, Rh-Del type can only be detected by an adsorption-elution technique, and it might be mistyped as Rh-negative.
The prevalence of Rh-Del has not been reported yet in Myanmar.
Method.
A total of 222 Rh-negative blood donors in the National Blood Center were tested for weak D and Rh-Del by indirect antihuman globulin and adsorption-elution method, respectively.
RhCE typing was performed among Rh-negative and Rh-Del.
Results.
Of them, 75.2% (167/222) were Rh-negative, 15.8% (35/222) were Rh-Del, and 9% (20/222) were weak D.
Of 202 blood donors (167 true Rh-negative and 35 Rh-Del), all of the Rh-Del positives were C-antigen-positive with 94.3% Ccee phenotype (33/35) and 5.7% CCee (2/35).
Most of the Rh-negative donors (80.2%) were ccee phenotype (134/167).
Conclusion.
About half of Rh-Del subjects were repeated donors, and attention was needed to avoid transfusion of truly Rh-negative patients to prevent alloimmunization.
It is recommended to do Rh-Del typing of Rh-negative donors who are C-antigen-positive and consider moving them to the Rh-positive pool.
Further study is needed to clarify the alloimmunization status for transfusion of Rh-Del blood to Rh-negative recipients.
Molecular markers for RhD-negative and D variants should be established in the Myanmar population to improve selection of antisera for Rh typing and enhance safety of the transfusion services.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wah, Saw Thu& Chi, Saung Nay& Kyaing, Kyi Kyi& Khin, Aye Aye& Aung, Thida. 2020. Serological Detection of Rh-Del Phenotype among Rh-Negative Blood Donors at National Blood Center, Yangon, Myanmar. Advances in Hematology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1126422
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wah, Saw Thu…[et al.]. Serological Detection of Rh-Del Phenotype among Rh-Negative Blood Donors at National Blood Center, Yangon, Myanmar. Advances in Hematology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1126422
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wah, Saw Thu& Chi, Saung Nay& Kyaing, Kyi Kyi& Khin, Aye Aye& Aung, Thida. Serological Detection of Rh-Del Phenotype among Rh-Negative Blood Donors at National Blood Center, Yangon, Myanmar. Advances in Hematology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1126422
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126422
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر