Lactobacillus iners Is Associated with Vaginal Dysbiosis in Healthy Pregnant Women: A Preliminary Study
المؤلفون المشاركون
Ling, Zongxin
Zheng, Nengneng
Guo, Renyong
Yao, Yinyu
Jin, Meiyuan
Cheng, Yiwen
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-23
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Vaginal dysbiosis has been identified to be associated with adverse pregnancy outcomes, such as preterm delivery and premature rupture of membranes.
However, the overall structure and composition of vaginal microbiota in different trimesters of the pregnant women has not been fully elucidated.
In this study, the physiological changes of the vaginal microbiota in healthy pregnant women were investigated.
A total of 83 healthy pregnant participants were enrolled, who are in the first, second, or third pregnancy trimester.
Quantitative real-time PCR was used to explore the abundant bacteria in the vaginal microbiota.
No significant difference in the abundance of Gardnerella, Atopobium, Megasphaera, Eggerthella, Leptotrichia/Sneathia, or Prevotella was found among different trimesters, except Lactobacillus.
Compared with the first pregnancy trimester, the abundance of L.
iners decreased in the second and third trimester while the abundance of L.
crispatus was increased in the second trimester.
Moreover, we also found that vaginal cleanliness is correlated with the present of Lactobacillus, Atopobium, and Prevotella and leukocyte esterase is associated with Lactobacillus, Atopobium, Gardnerella, Eggerthella, Leptotrichia/Sneathia, and Prevotella.
For those whose vaginal cleanliness raised or leukocyte esterase became positive, the richness of L.
iners increased, while that of L.
crispatus decreased significantly.
Our present data indicated that the altered vaginal microbiota, mainly Lactobacillus, could be observed among different trimesters of pregnancy and L.
iners could be considered as a potential bacterial marker for evaluating vaginal cleanliness and leukocyte esterase.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zheng, Nengneng& Guo, Renyong& Yao, Yinyu& Jin, Meiyuan& Cheng, Yiwen& Ling, Zongxin. 2019. Lactobacillus iners Is Associated with Vaginal Dysbiosis in Healthy Pregnant Women: A Preliminary Study. BioMed Research International،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1126457
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zheng, Nengneng…[et al.]. Lactobacillus iners Is Associated with Vaginal Dysbiosis in Healthy Pregnant Women: A Preliminary Study. BioMed Research International No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1126457
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zheng, Nengneng& Guo, Renyong& Yao, Yinyu& Jin, Meiyuan& Cheng, Yiwen& Ling, Zongxin. Lactobacillus iners Is Associated with Vaginal Dysbiosis in Healthy Pregnant Women: A Preliminary Study. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1126457
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126457
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر