Short-Time Antibacterial Effects of Dimethylaminododecyl Methacrylate on Oral Multispecies Biofilm In Vitro
المؤلفون المشاركون
Li, Mingyun
Zhou, Yujie
Wang, Suping
Zhou, Xuedong
Zou, Yiran
Peng, Xian
Ren, Biao
Xu, Hockin H. K.
Weir, Michael D.
Cheng, Lei
Chen, Yu
Han, Qi
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-21
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Quaternary ammonium compounds constitute a large group of antibacterial chemicals with a potential for inhibiting dental plaque.
The aims of this study were to evaluate short-time antibacterial and regulating effects of dimethylaminododecyl methacrylate (DMADDM) on multispecies biofilm viability, reformation, and bacterial composition in vitro.
DMADDM, chlorhexidine (CHX), and sodium fluoride (NaF) were chosen in the present study.
Streptococcus mutans, Streptococcus sanguinis, and Streptococcus gordonii were used to form multispecies biofilm.
Cytotoxicity assay was used to determine the optimal tested concentration.
3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and resazurin test of biofilm were conducted to study the biomass changes and metabolic changes of controlled multispecies biofilm.
Scanning electron microscopy (SEM) was used to observe biofilm images.
TaqMan real-time polymerase chain reaction was performed to evaluate the proportion change in multispecies biofilm of different groups.
Cytotoxicity assay showed that there existed a certain concentration application range for DMADDM, CHX, and NaF.
MTT assay and resazurin test results showed that DMADDM and CHX groups decreased multispecies biofilm growth and metabolic activity (p < 0.05), no matter after 1 min or 5 min direct contact killing or after 24 h regrowth.
The proportion of S.
mutans decreased steadily in DMADDM and CHX groups after 1 min and 5 min direct contact killing and 24 h regrowth, compared to control groups.
A novel DMADDM-containing solution was developed, achieving effective short-time antibacterial effects and regulation ability of biofilm formation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Yujie& Wang, Suping& Zhou, Xuedong& Zou, Yiran& Li, Mingyun& Peng, Xian…[et al.]. 2019. Short-Time Antibacterial Effects of Dimethylaminododecyl Methacrylate on Oral Multispecies Biofilm In Vitro. BioMed Research International،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1126730
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Yujie…[et al.]. Short-Time Antibacterial Effects of Dimethylaminododecyl Methacrylate on Oral Multispecies Biofilm In Vitro. BioMed Research International No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1126730
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Yujie& Wang, Suping& Zhou, Xuedong& Zou, Yiran& Li, Mingyun& Peng, Xian…[et al.]. Short-Time Antibacterial Effects of Dimethylaminododecyl Methacrylate on Oral Multispecies Biofilm In Vitro. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1126730
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126730
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر