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Fungal Keratitis: Epidemiology, Rapid Detection, and Antifungal Susceptibilities of Fusarium and Aspergillus Isolates from Corneal Scrapings
المؤلفون المشاركون
Palanisamy, Manikandan
Abdel-hadi, Ahmed
Randhir Babu Singh, Yendrembam
Revathi, Rajaraman
Anita, Raghavan
Banawas, Saeed
Bin Dukhyil, Abdul Aziz
Alshehri, Bader
Shobana, Coimbatore Subramanian
Panneer Selvam, Kanesan
Narendran, Venkatapathy
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-20
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Fungal aetiology of keratitis/corneal ulcer is considered to be one of the leading causes of ocular morbidity, particularly in developing countries including India.
More importantly, Fusarium and Aspergillus are reported commonly implicating corneal ulcer and against this background the present work was undertaken so as to understand the current epidemiological trend of the two fungal keratitis.
During the project period, a total of 500 corneal scrapings were collected from suspected mycotic keratitis patients, of which 411 (82.2%) were culture positive for bacteria, fungi, and parasites.
Among fungal aetiologies, Fusarium (216, 52.5% of 411) and Aspergillus (68, 16.5% of 411) were predominantly determined.
While the study revealed a male preponderance with both the fungal keratitis , it further brought out that polyene compounds (natamycin and amphotericin B) and azoles were active, respectively, against Fusarium spp.
and Aspergillus spp.
Additionally, 94.1% of culture proven Fusarium keratitis and, respectively, 100% and 63.6% of A.
flavus and A.
fumigatus were confirmed by multiplex PCR.
The sensitivity of the PCR employed in the present study was noted to be 10 fg/μl, 1 pg/μl, and 300 pg/μl of DNA, respectively, for Fusarium, A.
flavus, and A.
fumigatus.
Alarming fact was that Fusarium and Aspergillus regionally remained to be the common cause of mycotic keratitis and the Fusarium isolates had a higher antifungal resistance than Aspergillus strains against most of the test drugs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Palanisamy, Manikandan& Abdel-hadi, Ahmed& Randhir Babu Singh, Yendrembam& Revathi, Rajaraman& Anita, Raghavan& Banawas, Saeed…[et al.]. 2019. Fungal Keratitis: Epidemiology, Rapid Detection, and Antifungal Susceptibilities of Fusarium and Aspergillus Isolates from Corneal Scrapings. BioMed Research International،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1126738
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Palanisamy, Manikandan…[et al.]. Fungal Keratitis: Epidemiology, Rapid Detection, and Antifungal Susceptibilities of Fusarium and Aspergillus Isolates from Corneal Scrapings. BioMed Research International No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1126738
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Palanisamy, Manikandan& Abdel-hadi, Ahmed& Randhir Babu Singh, Yendrembam& Revathi, Rajaraman& Anita, Raghavan& Banawas, Saeed…[et al.]. Fungal Keratitis: Epidemiology, Rapid Detection, and Antifungal Susceptibilities of Fusarium and Aspergillus Isolates from Corneal Scrapings. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1126738
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126738
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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