Characteristics and Histological Types of Lupus Nephritis in a Jordanian Tertiary Medical Center
المؤلفون المشاركون
Farah, Randa I.
Dannoun, Ebtesam
Abu Shahin, Nisreen
AlRyalat, Saif Aldeen
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-03-25
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
Few reports of lupus nephritis (LN) from Jordan and the Middle East exist.
This study assessed the demographic, clinical, and basic laboratory characteristics of Jordanian patients with LN and correlations with the histological class of LN.
Methods.
This was a retrospective study of all patients who underwent kidney biopsy between 2007 and 2018 at a tertiary medical center in Jordan.
Patients’ demographic, clinical, laboratory, and pathological data were reviewed.
Results.
In total, 79 patients were included in this study [mean age, 29.95 ± 12.16 years; 11 men (13.9%), 68 women (86.1%)].
Asymptomatic proteinuria and hematuria were the most common presentations in LN patients at biopsy (59.5%).
The study revealed a significant difference in frequency of nephritic syndrome (p= 0.01) between sexes (10.3% female vs.
45.5% male).
Class IV was the most common pathological class of LN [37 (46.8%)], followed by class V [15 (19%)] and class III [10 (12.7%)].
Post hoc analysis of the associations between laboratory values and histopathological patterns revealed a significant correlation between class IV lupus and renal failure (p= 0.018) and class IV lupus and anti-DNA antibodies p= 0.030).
End-stage renal disease (ESRD) occurred in 25% of lupus nephritis cases.
There was an increased likelihood of ESRD among men than women (45% vs.
22%).
Overall mortality was 10%.
Conclusion.
Although some clinical and laboratory findings correlate with histological types of LN, clinical and laboratory parameters of Jordanian patients with LN are not predictive of the histological type, although differences with regional studies were noted.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Farah, Randa I.& Dannoun, Ebtesam& Abu Shahin, Nisreen& AlRyalat, Saif Aldeen. 2019. Characteristics and Histological Types of Lupus Nephritis in a Jordanian Tertiary Medical Center. BioMed Research International،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1127102
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Farah, Randa I.…[et al.]. Characteristics and Histological Types of Lupus Nephritis in a Jordanian Tertiary Medical Center. BioMed Research International No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1127102
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Farah, Randa I.& Dannoun, Ebtesam& Abu Shahin, Nisreen& AlRyalat, Saif Aldeen. Characteristics and Histological Types of Lupus Nephritis in a Jordanian Tertiary Medical Center. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1127102
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1127102
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر