Long-Term Outcomes among Kidney Transplant Recipients and after Graft Failure: A Single-Center Cohort Study in Brazil
المؤلفون المشاركون
Bicalho, Paula Rebello
Requião-Moura, Lúcio R.
Arruda, Érika Ferraz
Chinen, Rogerio
Mello, Luciana
Bertocchi, Ana Paula F.
Lamkowski Naka, Erika
Tonato, Eduardo José
Pacheco-Silva, Alvaro
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-02
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
The results of kidney transplantation are impacted by the categories of events responsible for patient death and graft failure.
The objective of this study was to evaluate the causes of death and graft failure and outcomes after graft failure among kidney transplant recipients.
Methodology.
A retrospective cohort study was conducted with 944 patients who underwent kidney transplantation.
Outcomes were categorized in a managed and hierarchical manner.
Results.
The crude mortality rate was 10.8% (n=102): in 35.3% cause of death was infection, in 30.4% cardiovascular disease, and in 15.7% neoplasia and in 6.8%, it was not possible to determine the cause of death.
The rate of graft loss was 10.6%.
The main causes of graft failure were chronic rejection (40%), acute rejection (18.3%), thrombosis (17.3%), and recurrence of primary disease (16.5%).
Failures due to an acute rejection occurred earlier than those due to chronic rejection and recurrence (p<0.0001).
As late causes of graft loss, death with the functioning kidney occurred earlier than recurrence and chronic rejection (p=0.008).
The outcomes after graft failure were retransplantation in 26.1% and death in 21.4%, at a mean of 25.5 and 21.4 months, respectively.
Conclusion.
It was possible to identify more than 90% of the events responsible for the deaths of transplanted patients, predominantly infectious and cardiovascular diseases.
Among the causes of graft failure, chronic and acute rejections and recurrence were the main causes of graft failure which were followed more frequently by retransplantation than by death on dialysis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bicalho, Paula Rebello& Requião-Moura, Lúcio R.& Arruda, Érika Ferraz& Chinen, Rogerio& Mello, Luciana& Bertocchi, Ana Paula F.…[et al.]. 2019. Long-Term Outcomes among Kidney Transplant Recipients and after Graft Failure: A Single-Center Cohort Study in Brazil. BioMed Research International،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1127113
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bicalho, Paula Rebello…[et al.]. Long-Term Outcomes among Kidney Transplant Recipients and after Graft Failure: A Single-Center Cohort Study in Brazil. BioMed Research International No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1127113
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bicalho, Paula Rebello& Requião-Moura, Lúcio R.& Arruda, Érika Ferraz& Chinen, Rogerio& Mello, Luciana& Bertocchi, Ana Paula F.…[et al.]. Long-Term Outcomes among Kidney Transplant Recipients and after Graft Failure: A Single-Center Cohort Study in Brazil. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1127113
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1127113
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر