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Efficacy of Stereotactic Body Radiotherapy for Recurrent or Residual Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization
المؤلفون المشاركون
Yao, Erhua
Chen, Jinghong
Zhao, Xiaofang
Zheng, Yinyan
Wu, Xianheng
Han, Fei
Huang, Hecheng
Liang, Ping
Liu, Jianmin
Wu, Fasheng
Lin, Lianxing
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-03-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Aim.
To evaluate the efficacy and toxicity of hypofractionated stereotactic body radiotherapy (SBRT) for patients with recurrent or residual hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE).
Methods.
Between June 2008 and July 2015, thirty-three patients with HCC were treated by SBRT.
There were 63 lesions in 33 patients.
A total dose of 39–45 Gy/3–5 fractions was delivered to the 70–80% isodose line.
Results.
Objective response rate (CR + PR) was 84.8% at 6 months.
The overall survival rate was 87.9%, 75.8%, 57.6%, and 45.5% at 6, 12, 18, and 24 months, respectively.
Median overall survival was 19 months.
At 3 months, AFP decreased by more than 75% in 51.5% of patients (17/33).
Overall survival was significantly different ( P < 0.00 1 ) between the group of patients for whom AFP decreased more than 75% and the group for whom AFP decreased by less than 75%.
The AFP-negative rate was 48.5% (16/33) after 6 months.
Eight patients (24.2%) had grade 1-2 transient fatigue, and 11 patients (33.3%) had grade 1-2 gastrointestinal reactions within 1 month.
Conclusion.
SBRT is a promising noninvasive and palliative treatment with acceptable toxicity for recurrent or residual HCC after TACE.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yao, Erhua& Chen, Jinghong& Zhao, Xiaofang& Zheng, Yinyan& Wu, Xianheng& Han, Fei…[et al.]. 2018. Efficacy of Stereotactic Body Radiotherapy for Recurrent or Residual Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1127346
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yao, Erhua…[et al.]. Efficacy of Stereotactic Body Radiotherapy for Recurrent or Residual Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1127346
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yao, Erhua& Chen, Jinghong& Zhao, Xiaofang& Zheng, Yinyan& Wu, Xianheng& Han, Fei…[et al.]. Efficacy of Stereotactic Body Radiotherapy for Recurrent or Residual Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1127346
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1127346
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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