Effects of Propranolol on Neurodevelopmental Outcomes in Patients with Infantile Hemangioma: A Case-Control Study
المؤلفون المشاركون
Wang, Chuan
Wang, Qi
Xiang, Bo
Chen, Siyuan
Xiong, Fei
Ji, Yi
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-25
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
The aim of this study was to examine whether oral propranolol has any effect on neurodevelopment outcomes in young children with problematic infantile hemangiomas (IHs).
Methods.
Thirty-six children with a diagnosis of problematic IH who were treated with oral propranolol were compared with 34 healthy children with no history of propranolol therapy.
Patients received propranolol therapy for at least 3 months.
Gesell developmental schedules (GDS) were used to evaluate neurodevelopment outcomes in the two groups.
The scores of each GDS domain were compared between the two groups.
Results.
There were no significant differences in developmental quotient (DQ) values for any of the five domains between the patients and healthy controls (P<0.05).
Multiple stepwise regression analyses showed that none of the domains in the control group were influenced by the children’s gender or age (P<0.05).
In addition, we found that gender, age at the initiation of therapy, age at the time of the neurodevelopment test, and treatment duration had no effect on any domain of the GDS in the patient group (P>0.05).
Conclusion.
Propranolol has no obvious effect on neurodevelopmental outcomes in children.
Early treatment and treatment duration had no negative effect on central nervous system (CNS) development.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Chuan& Wang, Qi& Xiang, Bo& Chen, Siyuan& Xiong, Fei& Ji, Yi. 2018. Effects of Propranolol on Neurodevelopmental Outcomes in Patients with Infantile Hemangioma: A Case-Control Study. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1127549
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Chuan…[et al.]. Effects of Propranolol on Neurodevelopmental Outcomes in Patients with Infantile Hemangioma: A Case-Control Study. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1127549
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Chuan& Wang, Qi& Xiang, Bo& Chen, Siyuan& Xiong, Fei& Ji, Yi. Effects of Propranolol on Neurodevelopmental Outcomes in Patients with Infantile Hemangioma: A Case-Control Study. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1127549
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1127549
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر