Age at Menopause and Risk of Developing Endometrial Cancer: A Meta-Analysis
المؤلفون المشاركون
Wu, Yanjun
Sun, Wenjun
Liu, Hui
Zhang, Dongfeng
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-05-29
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Object.
The association of age at menopause with endometrial cancer remains controversial.
Therefore, we quantitatively summarized the evidence from observational studies with a meta-analysis.
Methods.
We searched PubMed, Web of Science, Embase, Medline, Chinese National Knowledge Infrastructure (CNKI), and Wan Fang Med online up to March 2019, and all eligible case-control and cohort studies were included in the study.
Pooled relative risks (RRs) with 95% confidence intervals (CIs) were calculated using the random-effects model.
The dose-response relationship was assessed by restricted cubic spline model.
The heterogeneity among studies was evaluated by I2.
Metaregression was used to explore the potential sources of between-study heterogeneity.
Egger’s test was used to estimate publication bias.
Results.
Eighteen articles including 957242 subjects with 4781 cases were included in the meta-analysis.
The pooled RR (95%CI) of endometrial cancer for the highest versus the lowest age at menopause was 1.89 (95%CI: 1.58-2.26).
For dose-response analysis, a nonlinear relationship was found between age at menopause and endometrial cancer, and the positive association became statistically significant when age at menopause was greater than 46.5 years old.
Conclusions.
This meta-analysis suggested that age at menopause was positively associated with endometrial cancer.
For women whose menopausal age over 46.5 years old, the risk of endometrial cancer increased with the age at menopause.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Yanjun& Sun, Wenjun& Liu, Hui& Zhang, Dongfeng. 2019. Age at Menopause and Risk of Developing Endometrial Cancer: A Meta-Analysis. BioMed Research International،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1128001
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Yanjun…[et al.]. Age at Menopause and Risk of Developing Endometrial Cancer: A Meta-Analysis. BioMed Research International No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1128001
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Yanjun& Sun, Wenjun& Liu, Hui& Zhang, Dongfeng. Age at Menopause and Risk of Developing Endometrial Cancer: A Meta-Analysis. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1128001
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128001
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر