Evaluation of Vascular Endothelial Growth Factor A and Selected Parameters of Coagulation and Fibrinolysis in a Group of Patients with Subarachnoid Haemorrhage
المؤلفون المشاركون
Malinowski, Bartosz
Wiciński, Michał
Al Drawi, Abu Sitta
Stolarek, Wioleta
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-07-08
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction.
Subarachnoid hemorrhage (SAH) is currently one of the most serious diseases of the central nervous system.
To reduce the negative consequences of SAH and help clinicians to assess the patient’s condition, there are attempts to search for new diagnostic markers, which quickly and accurately allow for the proper diagnosis.
The aim of this research was the concentration and activity of Vascular Endothelial Growth Factor A (VEGF-A) and selected parameters of coagulation and fibrinolysis in the blood of patients with SAH.
Serum levels of VEGF-A in patients diagnosed with SAH are measured to assess the correlation between VEGF-A and the clinical condition of patient.
This may help with proper therapeutics and better prognosis.
Methods.
The study involved 85 patients with subarachnoid hemorrhage.
The control group consisted of 45 healthy subjects, sex and age matched.
The following parameters were determined: APTT (Activated Partial Thromboplastin Time), INR (International Normalized Ratio), D-dimers and fibrinogen concentration, and the concentration of VEGF-A by ELISA (R&D USA).
Results.
The average concentration of VEGF-A in the study group was significantly lower compared to the control group.
The D-dimer concentration was higher in patients with SAH but the difference was not significant.
Coagulation parameters such as INR, APTT, and fibrinogen did not show significant differences between investigated groups.
Conclusions.
VEGF-A cannot be an independent marker of SAH.
Selected parameters of coagulation and fibrinolysis such as D-dimers, INR, APTT, and fibrinogen should not be used as markers of SAH.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wiciński, Michał& Al Drawi, Abu Sitta& Malinowski, Bartosz& Stolarek, Wioleta. 2019. Evaluation of Vascular Endothelial Growth Factor A and Selected Parameters of Coagulation and Fibrinolysis in a Group of Patients with Subarachnoid Haemorrhage. BioMed Research International،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1128121
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wiciński, Michał…[et al.]. Evaluation of Vascular Endothelial Growth Factor A and Selected Parameters of Coagulation and Fibrinolysis in a Group of Patients with Subarachnoid Haemorrhage. BioMed Research International No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1128121
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wiciński, Michał& Al Drawi, Abu Sitta& Malinowski, Bartosz& Stolarek, Wioleta. Evaluation of Vascular Endothelial Growth Factor A and Selected Parameters of Coagulation and Fibrinolysis in a Group of Patients with Subarachnoid Haemorrhage. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1128121
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128121
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر