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A Nomogram Predicting Microvascular Invasion Risk in BCLC 0A Hepatocellular Carcinoma after Curative Resection
المؤلفون المشاركون
Gao, Shuai-Xiang
Liao, Rui
Wang, Hua-Qiang
Liu, Dan
Luo, Fang
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-07-25
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Numerous studies have shown that hepatocellular carcinoma (HCC) without microvascular invasion (MVI) may have better outcomes.
This study established a preoperative MVI risk nomogram mainly incorporating three related risk factors of MVI in BCLC 0/A HCC after surgery.
Methods.
Independent predictors for the risk of MVI were investigated, and an MVI risk nomogram was established based on 60 patients in the training group who underwent curative hepatectomy for BCLC 0/A HCC and validated using a dataset in the validation group.
Results.
Univariate analysis in the training group showed that hepatitis viral B (HBV) DNA (P=0.034), tumor size (P<0.001), CT value in the venous phase (P=0.039), CT value in the delayed phase (P=0.017), peritumoral enhancement (P=0.013), visible small blood vessels in the arterial phase (P=0.002), and distance from the tumor to the inferior vena cava (IVC) (DTI, P=0.004) were risk factors significantly associated with the presence of MVI.
According to multivariate analysis, the independent predictive factors of MVI, including tumor size (P=0.002), CT value in the delayed phase (P=0.018), and peritumoral enhancement (P=0.057), were incorporated in the corresponding nomogram.
The nomogram displayed an unadjusted C-index of 0.851 and a bootstrap-corrected C-index of 0.832.
Calibration curves also showed good agreement on the presence of MVI.
ROC curve analyses showed that the nomogram had a large AUC (0.851).
Conclusions.
The proposed nomogram consisting of tumor size, CT value in the delayed phase, and peritumoral enhancement was associated with MVI risk in BCLC 0/A HCC following curative hepatectomy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gao, Shuai-Xiang& Liao, Rui& Wang, Hua-Qiang& Liu, Dan& Luo, Fang. 2019. A Nomogram Predicting Microvascular Invasion Risk in BCLC 0A Hepatocellular Carcinoma after Curative Resection. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1128414
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gao, Shuai-Xiang…[et al.]. A Nomogram Predicting Microvascular Invasion Risk in BCLC 0A Hepatocellular Carcinoma after Curative Resection. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1128414
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gao, Shuai-Xiang& Liao, Rui& Wang, Hua-Qiang& Liu, Dan& Luo, Fang. A Nomogram Predicting Microvascular Invasion Risk in BCLC 0A Hepatocellular Carcinoma after Curative Resection. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1128414
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128414
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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