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Evaluation of a Porous Bioabsorbable Interbody Mg-Zn Alloy Cage in a Goat Cervical Spine Model
المؤلفون المشاركون
Shao, Minghao
Lu, Feizhou
Wang, Hongli
Jiang, Jianyuan
Ma, Xiaosheng
Xia, Xinlei
Xu, Haocheng
Zhang, Fan
Geng, Fang
Xu, Shun
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-25
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Purpose.
Bioabsorbable Mg-based implants were previously assessed due to their intrinsic advantages, but Mg-based cage related research is limited.
The specific blood supply and stress of the intervertebral environment can affect the function of Mg-based implants.
The objective of this study was to investigate the performance of a bioabsorbable Mg-Zn alloy cage in anterior cervical discectomy and fusion (ACDF) and evaluate the control of degradation of the Mg-Zn cage surface modified by microarc oxidation (MAO) technology containing Si under an intervertebral microenvironment.
Methods.
Twenty-four goats were divided into four groups according to the experimental period and all underwent ACDF at C2-3 and C4-5 with porous Mg-Zn cage covered with a MAO/Si-containing coating in one intervertebral space and with autologous iliac bone in another space.
After 3, 6, 12, or 24 weeks after operation, the cervical spine specimens were harvested to evaluate the biocompatibility, fusion status, and degradation conditions using blood analysis, radiology, biomechanical testing, histology, and micro-CT.
Results.
The Mg-Zn cages showed ideal biocompatibility and biomechanical characterization; however, the fusion state, as evaluated with radiology and histology, was not acceptable.
Modified by the MAO/Si-containing coating, the degradation rate of the Mg-Zn cages was controllable but slower than expected.
Conclusion.
MAO/Si-containing coating Mg-Zn alloy cages demonstrated excessive control of degradation and fusion failure after 24 weeks postoperatively.
We conclude that further studies should be designed to improve the using of Mg-based materials at the intervertebral space.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Haocheng& Zhang, Fan& Wang, Hongli& Geng, Fang& Shao, Minghao& Xu, Shun…[et al.]. 2018. Evaluation of a Porous Bioabsorbable Interbody Mg-Zn Alloy Cage in a Goat Cervical Spine Model. BioMed Research International،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1128818
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Haocheng…[et al.]. Evaluation of a Porous Bioabsorbable Interbody Mg-Zn Alloy Cage in a Goat Cervical Spine Model. BioMed Research International No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1128818
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Haocheng& Zhang, Fan& Wang, Hongli& Geng, Fang& Shao, Minghao& Xu, Shun…[et al.]. Evaluation of a Porous Bioabsorbable Interbody Mg-Zn Alloy Cage in a Goat Cervical Spine Model. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1128818
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128818
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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