Pseudomonas aeruginosa Isolates from Spanish Children: Occurrence in Faecal Samples, Antimicrobial Resistance, Virulence, and Molecular Typing
المؤلفون المشاركون
Ruiz-Roldán, Lidia
Bellés, Alba
Bueno, Jessica
Azcona-Gutiérrez, José Manuel
Rojo-Bezares, Beatriz
Torres, Carmen
Castillo, F. Javier
Sáenz, Yolanda
Seral, Cristina
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-11
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Pseudomonas aeruginosa is a major opportunistic human pathogen, responsible for nosocomial infections and infections in patients with impaired immune systems.
Little data exist about the faecal colonisation by P.
aeruginosa isolates in healthy humans.
The occurrence, antimicrobial resistance phenotype, virulence genotype, and genetic lineages of P.
aeruginosa from faecal samples of children from two different Spanish regions were characterised.
Seventy-two P.
aeruginosa were isolated from 1,443 faecal samples.
Low antimicrobial resistance levels were detected: ceftazidime (8%), cefepime (7%), aztreonam (7%), gentamicin (3%), ciprofloxacin (1%), and imipenem (1%); susceptibility to meropenem, amikacin, tobramycin, levofloxacin, and colistin.
Four multidrug-resistant strains were found.
Important differences were detected between both geographical regions.
Forty-one sequence types were detected among the 48 tested strains.
Virulence and quorum sensing genes were analysed and 13 virulotypes were detected, being 26 exoU-positive strains.
Alteration in protein OprD showed eight different patterns.
The unique imipenem-resistant strain showed a premature stop codon in OprD.
Intestinal colonisation by P.
aeruginosa, mainly by international clones (as ST244, ST253, and ST274), is an important factor for the systemic infections development and the environmental dissemination.
Periodic active surveillance is useful to identify these community human reservoirs and to control the evolution of antibiotic resistance and virulence activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ruiz-Roldán, Lidia& Bellés, Alba& Bueno, Jessica& Azcona-Gutiérrez, José Manuel& Rojo-Bezares, Beatriz& Torres, Carmen…[et al.]. 2018. Pseudomonas aeruginosa Isolates from Spanish Children: Occurrence in Faecal Samples, Antimicrobial Resistance, Virulence, and Molecular Typing. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1128862
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ruiz-Roldán, Lidia…[et al.]. Pseudomonas aeruginosa Isolates from Spanish Children: Occurrence in Faecal Samples, Antimicrobial Resistance, Virulence, and Molecular Typing. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1128862
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ruiz-Roldán, Lidia& Bellés, Alba& Bueno, Jessica& Azcona-Gutiérrez, José Manuel& Rojo-Bezares, Beatriz& Torres, Carmen…[et al.]. Pseudomonas aeruginosa Isolates from Spanish Children: Occurrence in Faecal Samples, Antimicrobial Resistance, Virulence, and Molecular Typing. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1128862
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128862
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر