Effect of Hypoxia-Inducible Factor 1α on Early Healing in Extraction Sockets
المؤلفون المشاركون
Song, Je Seon
Jeon, Mijeong
Thoma, Daniel Stefan
Jung, Ui-Won
Lim, Hyun-Chang
Lee, Sang-Kyou
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The aim of the present study was to investigate the effect of hypoxia-inducible factor 1α (HIF1A) on the early healing (4 weeks) of extraction sockets exhibiting partial loss of the labial bone.
Two extraction sockets of the maxillary incisors from each of six dogs were assigned to two treatment modalities: deproteinized bovine bone mineral (i) with 10% collagen (DBBM-C) soaked with HIF1A and covered by a collagen membrane (CM) (HIF group) or (ii) treated with DBBM-C only and covered by a CM (control group).
Microcomputed tomography revealed some degree of collapse of the labial contour.
The totally augmented volume and new bone volume did not differ significantly between two groups (P>0.05).
The histological analysis revealed that the apical area of the socket was mostly filled with newly formed bone, while there was less newly formed bone in the coronal area and incomplete cortex formation.
The histomorphometric analysis revealed that the area of newly formed bone was significantly larger in the HIF group than the control group (12.16±3.04 versus 9.48±2.01 mm2, P<0.05), while there was no significant intergroup difference in the total augmented area.
In conclusion, even though DBBM-C soaked with HIF1A enhanced histomorphometric bone formation, this intervention did not demonstrate superiority in preventing ridge shrinkage compared to DBBM-C alone.
Clinical relevance of these findings should be further studied.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lim, Hyun-Chang& Thoma, Daniel Stefan& Jeon, Mijeong& Song, Je Seon& Lee, Sang-Kyou& Jung, Ui-Won. 2018. Effect of Hypoxia-Inducible Factor 1α on Early Healing in Extraction Sockets. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1128977
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lim, Hyun-Chang…[et al.]. Effect of Hypoxia-Inducible Factor 1α on Early Healing in Extraction Sockets. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1128977
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lim, Hyun-Chang& Thoma, Daniel Stefan& Jeon, Mijeong& Song, Je Seon& Lee, Sang-Kyou& Jung, Ui-Won. Effect of Hypoxia-Inducible Factor 1α on Early Healing in Extraction Sockets. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1128977
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128977
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر