Association between Participants’ Characteristics, Patient-Reported Outcomes, and Clinical Outcomes in Youth with Sickle Cell Disease
المؤلفون المشاركون
Badawy, Sherif M.
Barrera, Leonardo
Cai, Stephanie
Thompson, Alexis A.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-18
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Sickle cell disease (SCD) is a chronic debilitating illness.
SCD-related complications result in substantial impairment in quality of life (QOL).
Our study objective was to assess the relationship of participants’ characteristics, QOL, hydroxyurea adherence, and SCD-related clinical outcomes in youth with SCD.
Procedure.
A single-center cross-sectional study.
Thirty-four youth with SCD enrolled from clinic between January and December 2015.
Participants completed PROMIS® measures and ©Modified Morisky Adherence Scale.
Results.
Participants had a mean age of 14.8 (SD 2.9) years and 41% were female.
Participants’ age correlated with fatigue (rs=0.48; P=0.006), pain (rs=0.32; P=0.07), and anxiety (rs=0.33; P=0.06) scores.
Participants with chronic pain had worse upper extremity physical function (P=0.05), pain (P=0.04), anxiety (P=0.05), and depression (P=0.05).
Males reported significantly higher hydroxyurea adherence (5.4 versus 3.6, P=0.02) compared to females.
Participants with chronic pain had more frequent hospitalizations (P=0.02), emergency room visits (P=0.04), and longer total length of hospital stays over 12-month period (P=0.01).
Conclusions.
Older and female participants had worse QOL scores, and males reported higher hydroxyurea adherence.
Participants with chronic pain reported significant impairment in different QOL domains and had increased healthcare utilization.
Future longitudinal studies examining the relationship between participants’ characteristics, QOL, hydroxyurea adherence, and SCD-related clinical outcomes are needed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Badawy, Sherif M.& Barrera, Leonardo& Cai, Stephanie& Thompson, Alexis A.. 2018. Association between Participants’ Characteristics, Patient-Reported Outcomes, and Clinical Outcomes in Youth with Sickle Cell Disease. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1129038
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Badawy, Sherif M.…[et al.]. Association between Participants’ Characteristics, Patient-Reported Outcomes, and Clinical Outcomes in Youth with Sickle Cell Disease. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1129038
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Badawy, Sherif M.& Barrera, Leonardo& Cai, Stephanie& Thompson, Alexis A.. Association between Participants’ Characteristics, Patient-Reported Outcomes, and Clinical Outcomes in Youth with Sickle Cell Disease. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1129038
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129038
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر