Growth Media Affect Assessment of Antimicrobial Activity of Plant-Derived Polyphenols
المؤلفون المشاركون
Wu, Christine D.
Xu, Xin
Ou, Zhen M.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-09
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
This study aimed to investigate the effects of different microbial growth media on the laboratory assessment of antimicrobial activity of natural polyphenolic compounds.
The inhibition of the tea polyphenol EGCG on growth of selected oral microorganisms was evaluated in complex media and a protein-free chemically defined medium (CDM).
Other antimicrobial agents (polyphenolic grape seed extract, plant alkaloid berberine, methyl salicylate, and chlorhexidine gluconate) were also tested in the study.
The presence of proteins and their effects on the antimicrobial activity of EGCG were investigated by the addition of BSA to the CDM.
The MICs of EGCG against test oral microorganisms were 4 to 64 times higher in complex media than in CDM.
The polyphenolic grape seed extract exhibited similar discrepancies.
However, the MICs of the nonpolyphenolic compounds (berberine, methyl salicylate, and chlorhexidine) were not significantly different between the two growth media.
The MIC of EGCG against S.
mutans UA159 in CDM with added BSA was 16 times higher than that in CDM alone.
Therefore, nonproteinaceous CDM should be used to avoid interference of proteins with the active ingredients when testing the antimicrobial activity of plant-derived polyphenolic compounds against microorganisms.
This will also minimize the discrepancies noted in results obtained by different investigators.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Xin& Ou, Zhen M.& Wu, Christine D.. 2018. Growth Media Affect Assessment of Antimicrobial Activity of Plant-Derived Polyphenols. BioMed Research International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1129052
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Xin…[et al.]. Growth Media Affect Assessment of Antimicrobial Activity of Plant-Derived Polyphenols. BioMed Research International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1129052
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Xin& Ou, Zhen M.& Wu, Christine D.. Growth Media Affect Assessment of Antimicrobial Activity of Plant-Derived Polyphenols. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1129052
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129052
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر