Circulating Galectin-3 and Atrial Fibrillation Recurrence after Catheter Ablation: A Meta-Analysis
المؤلفون المشاركون
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Galectin-3 (Gal-3) is involved in fibrosis and heart failure.
However, epidemiological studies evaluating the association between Gal-3 and atrial fibrillation (AF) recurrence after catheter ablation showed inconsistent results.
We conducted a meta-analysis to comprehensively evaluate the relationship between baseline circulating Gal-3 levels and AF recurrence in patients undergoing catheter ablation.
Methods.
Relevant studies were identified by systematically searching the PubMed and Embase databases.
A random-effect model was used to synthesize the results.
Sensitivity analyses, performed by omitting one study at a time, were used to evaluate the robustness of the results.
Results.
Seven prospective cohort studies including 645 AF patients were included.
Within a follow-up duration of up to 18 months, 244 patients developed AF recurrence.
Pooled results showed that baseline circulating Gal-3 levels were significantly higher in patients with AF recurrence compared to those without (standardized mean difference: 0.74; 95% confidence interval (CI): 0.21 - 1.27; p = 0.007; I2 = 89%).
Moreover, higher baseline Gal-3 levels were independently associated with a significantly higher risk of AF recurrence after catheter ablation (risk ratio: 1.17 per unit of Gal-3; 95% CI: 1.01 - 1.35; p = 0.03; I2 = 40%), which was independent of age, gender, and left atrial dimension.
Sensitivity analyses did not significantly affect the results.
However, there was a significant publication bias for predicting efficacy of associating preprocedural Gal-3 levels with AF recurrence.
Conclusions.
Higher preprocedural Gal-3 levels may be associated with increased risk of AF recurrence in patients undergoing catheter ablation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Guangping& Wu, Yongquan. 2019. Circulating Galectin-3 and Atrial Fibrillation Recurrence after Catheter Ablation: A Meta-Analysis. Cardiovascular Therapeutics،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1129165
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Guangping& Wu, Yongquan. Circulating Galectin-3 and Atrial Fibrillation Recurrence after Catheter Ablation: A Meta-Analysis. Cardiovascular Therapeutics No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1129165
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Guangping& Wu, Yongquan. Circulating Galectin-3 and Atrial Fibrillation Recurrence after Catheter Ablation: A Meta-Analysis. Cardiovascular Therapeutics. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1129165
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129165
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر